Evidence map›Paper›PMID 34778796›Full record

ArticleBlood cancer discovery2021

How to Provide the Needed Protection from COVID-19 to Patients with Hematologic Malignancies.

Antoni Ribas, Madhav V Dhodapkar, Katie M Campbell, Faith E Davies, Steven D Gore, Ronald Levy, Lee M Greenberger

Open access · bronzeAbstract read
In one paragraph

Article in Blood cancer discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Antoni RibasDepartment of Medicine and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California. aribas@mednet.ucla.edu.ORCID 0000-0003-3669-8458
Madhav V DhodapkarDepartment of Hematology and Medical Oncology at the Winship Cancer Institute of Emory University, Atlanta, Georgia.
Katie M CampbellDepartment of Medicine and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California.ORCID 0000-0001-6491-4432
Faith E DaviesDepartment of Medicine and Perlmutter Cancer Center, New York University, New York, New York.
Steven D GoreAACR Hematologic Malignancies Task Force, Philadelphia, Pennsylvania.
Ronald LevyAACR Hematologic Malignancies Task Force, Philadelphia, Pennsylvania.ORCID 0000-0003-2061-0650
Lee M GreenbergerThe Leukemia & Lymphoma Society, Rye Brook, New York.
University of California, Los Angeles · USAmerican Association For Cancer Research · USEmory University · USLeukemia and Lymphoma Society · USNational Institutes of Health · USPalo Alto University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Next Generation Cancer Immunotherapies to Defeat MelanomaR35CA197633 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANTONI RIBAS · 2015 to 2026
$10.4M
HARNESSING HOST RESPONSE TO PREVENT MYELOMAR35CA197603 · NCI · YALE UNIVERSITY · PI DHODAPKAR, MADHAV V · 2016 to 2022
$5.8M
NCATS NIH HHS UL1 TR001863NCI NIH HHS R35 CA197603NCI NIH HHS R35 CA197633
6 · The paper itself

Abstract

Patients with hematologic malignancies are particularly vulnerable to COVID-19 infections, and upon a pooled data analysis of 24 publications, there is evidence that they have suboptimal antibody responses to COVID-19 vaccination and boosters. To provide them the needed additional protection from COVID-19, it is imperative to achieve a 100% full immunization rate in health care workers and adult caretakers, and to foster research to test higher doses and repeated rounds of COVID-19 vaccines and the use of passive immune prophylaxis and therapy.

Indexed as

COVID-19Hematologic NeoplasmsAdultCOVID-19 VaccinesHumansImmunization, SecondarySARS-CoV-2COVID-19 Vaccines

Identifiers

PMID34778796
PMCPMC8580613
OpenAlexW3200272276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.