Evidence map›Paper›PMID 34778795›Full record

ArticlePHAGE (New Rochelle, N.Y.)2021

Solvent Extraction of

Jordyn Michalik-Provasek, Harley Parker, Lauren Lessor, Jason J Gill

Abstract read
In one paragraph

Article in PHAGE (New Rochelle, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jordyn Michalik-ProvasekDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, Texas, USA.ORCID https://orcid.org/0000-0002-0237-8918
Harley ParkerDepartment of Medicine, Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-6314-6854
Lauren LessorCenter for Phage Technology, Texas A&M AgriLife Research and Texas A&M University, College Station, Texas, USA.
Jason J GillDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, Texas, USA.

Funding

Development of therapeutic bacteriophages against carbapenemase-resistant Klebsiella pneumoniaeR33AI121689 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI GILL, JASON J., WALSH, THOMAS · 2018 to 2020
$1.4M
NIAID NIH HHS R33 AI121689
6 · The paper itself

Abstract

Antimicrobial resistance in pathogenic bacteria is increasing worldwide. One solution to this crisis is bacteriophage therapy, a treatment that harnesses naturally occurring bacterial viruses to invade and lyse antimicrobial resistant bacterial hosts. In Gram-negative hosts, a by-product of bacteriophage production is bacterial endotoxin, which can cause serious immune reactions

Indexed as

antimicrobial resistancebacteriophage purificationbacteriophage therapyendotoxin removalKlebsiella pneumoniae

Identifiers

PMID34778795
PMCPMC8574134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.