ArticleRadiology. Cardiothoracic imaging2021
Evaluation of Coronary Plaques and Stents with Conventional and Photon-counting CT: Benefits of High-Resolution Photon-counting CT.
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Article in Radiology. Cardiothoracic imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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52citing papers in PubMed, 1 pooled it
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Photon-counting CT versus energy-integrating detectors for cardiac imaging: a systematic review of evidence from in vivo human studies on image quality and radiation dose.BMC medical imaging · 2025Pooled it
- Photon-counting detector CT vs energy-integrating detector CT for the diagnosis of arterial dissection in the cervicocerebral region: A single-center case series.Radiology case reports · 2026Article
- Application and Development of Spectral CT in Target Delineation for Lung Cancer Radiotherapy.Diagnostics (Basel, Switzerland) · 2026Review
- Photon-counting computed tomography in coronary artery bypass grafting planning and follow-up: a narrative review of a high-resolution adjunct to invasive angiography.Journal of thoracic disease · 2026Review
- Feasibility of On-Site CT-FFR Analysis in Ruling Out In-Stent Restenosis on Cardiac PCCT.Journal of cardiovascular development and disease · 2026Article
- Design of a next-generation conventional scintillator x-ray detector: Improved spatial resolution and fill factor.Medical physics · 2026Article
- Ultra-high spatial resolution at photon-counting computed tomography: technical insights and sustainable applications in cardiothoracic imaging.European radiology experimental · 2026Review
- Assessment of Image Quality Performance of a Photon-Counting Computed Tomography Scanner Approved for Whole-Body Clinical Applications.Sensors (Basel, Switzerland) · 2025Article
- Spectral ultrahigh-resolution photon-counting CT for coronary stent imaging: evaluation in a dynamic phantom.European radiology experimental · 2025Article
- Impact of vessel size, dose levels, and body habitus on iodine quantification in cardiovascular photon-counting computed tomography.The British journal of radiology · 2025Article
- Multilayer and crushed stent visualization using photon- counting detector computed tomography - a proof of concept.Scientific reports · 2025Article
- Joint CT reconstruction of anatomy and implants using a mixed prior model.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Computed Tomography and Coronary Plaque Analysis.Tomography (Ann Arbor, Mich.) · 2025Review
- Ultra-high-resolution 40 keV virtual monoenergetic imaging using spectral photon-counting CT in high-risk patients for coronary stenoses.European radiology · 2025Article
- Influence of virtual monoenergetic reconstructions on coronary CT angiography-based fractional flow reserve with photon-counting detector CT: intra-individual comparison with energy-integrating detector CT.Insights into imaging · 2025Article
- Value of Ultrahigh-Resolution Photon-Counting Detector Computed Tomography in Cardiac Imaging.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Computed Tomography Angiography in the Catheterization Laboratory: A Guide Towards Optimizing Coronary Interventions.Journal of cardiovascular development and disease · 2025Review
- Health improvements by understanding residual risk in coronary artery disease and new targets for prevention/treatment: rationale and research protocol of the HURRICANE project.European heart journal open · 2025Article
- In-Stent Restenosis in Peripheral Arterial Disease: Ultra-High-Resolution Photon-Counting Versus Third-Generation Dual-Source Energy-Integrating Detector CT Phantom Study in Seven Different Stent Types.Cardiovascular and interventional radiology · 2025Article
- Coronary atherosclerotic plaque characterization with silicon-based photon-counting computed tomography (CT): A simulation-based feasibility study.Medical physics · 2024Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Jayasai R RajagopalCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID https://orcid.org/0000-0001-8529-5597
Faraz FarhadiCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0002-6958-0811
Taylor RichardsCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
Moozhan NikpanahCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0001-7428-0226
Pooyan SahbaeeCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
Sujata M ShanbhagCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
W Patricia BandettiniCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0003-2342-5637
Babak SabouryCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0002-8632-6292
Ashkan A MalayeriCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID https://orcid.org/0000-0002-4442-7343
William F PritchardCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0001-5805-5344
Elizabeth C JonesCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
Ehsan SameiCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID 0000-0001-7451-3309
Marcus Y ChenCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).ORCID https://orcid.org/0000-0003-0743-9369
Advanced Imaging Research (United States) · USNational Institutes of Health · US
Funding
Cardiovascular CT Clinical ResearchZIAHL006220 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CHEN, MARCUS · 2017 to 2025
$22.5MCenter for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7MSimulation Tools for Dynamic CTR01EB001838 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2005 to 2023
$6.9MPrecision Cardiac CT: Development of a Computational Platform for Optimizing ImagingR01HL131753 · NHLBI · DUKE UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2017 to 2020
$2.7MIntramural NIH HHS ZIA HL006220Intramural NIH HHS ZID BC011242NHLBI NIH HHS R01 HL131753NIBIB NIH HHS R01 EB001838
Abstract
purposeTo compare the performance of energy-integrating detector (EID) CT, photon-counting detector CT (PCCT), and high-resolution PCCT (HR-PCCT) for the visualization of coronary plaques and reduction of stent artifacts in a phantom model. MATERIALS AND
methodsAn investigational scanner with EID and PCCT subsystems was used to image a coronary artery phantom containing cylindrical probes simulating different plaque compositions. The phantom was imaged with and without coronary stents using both subsystems. Images were reconstructed with a clinical cardiac kernel and an additional HR-PCCT kernel. Regions of interest were drawn around probes and evaluated for in-plane diameter and a qualitative comparison by expert readers. A linear mixed-effects model was used to compare the diameter results, and a Shrout-Fleiss intraclass correlation coefficient was used to assess consistency in the reader study.
resultsComparing in-plane diameter to the physical dimension for nonstented and stented phantoms, measurements of the HR-PCCT images were more accurate (nonstented: 4.4% ± 1.1 [standard deviation], stented: -9.4% ± 4.6) than EID (nonstented: 15.5% ± 4.0, stented: -19.5% ± 5.8) and PCCT (nonstented: 19.4% ± 2.5, stented: -18.3% ± 4.4). Our analysis of variance found diameter measurements to be different across image groups for both nonstented and stented cases (
conclusionDespite increased noise, HR-PCCT images were able to better visualize coronary plaques and reduce stent artifacts compared with EID or PCCT reconstructions.
Indexed as
CardiacCT-Spectral Imaging (Dual Energy)Phantom StudiesPhysicsTechnology Assessment
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