Evidence map›Paper›PMID 34778775›Full record

ArticleRSC medicinal chemistry2021

Virtual screening and

Ronel Müller, Tiaan M Gerwel, Magambo Phillip Kimuda, Özlem Tastan Bishop, Clinton G L Veale, Heinrich C Hoppe

Abstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronel MüllerSchool of Chemistry and Physics, Pietermaritzburg Campus, University of KwaZulu-Natal Private Bag X01 Scottsville 3209 South Africa VealeC@ukzn.ac.za.
Tiaan M GerwelFaculty of Pharmacy, Rhodes University Makhanda 6140 South Africa.
Magambo Phillip KimudaResearch Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University Makhanda 6140 South Africa.ORCID https://orcid.org/0000-0003-3911-8359
Özlem Tastan BishopResearch Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University Makhanda 6140 South Africa.
Clinton G L VealeSchool of Chemistry and Physics, Pietermaritzburg Campus, University of KwaZulu-Natal Private Bag X01 Scottsville 3209 South Africa VealeC@ukzn.ac.za.ORCID https://orcid.org/0000-0002-4043-7106
Heinrich C HoppeDepartment of Biochemistry and Microbiology, Rhodes University Makhanda 6140 South Africa H.Hoppe@ru.ac.za.ORCID https://orcid.org/0000-0003-4409-1955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HPPK, which directly precedes DHPS in the folate biosynthetic pathway, is a promising but chronically under-exploited anti-microbial target. Here we report the identification of new

Identifiers

PMID34778775
PMCPMC8528203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.