Evidence map›Paper›PMID 34778772›Full record

ArticleRSC medicinal chemistry2021

It takes two to tango: synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity.

Daisy J B Lima, Renata G Almeida, Guilherme A M Jardim, Breno P A Barbosa, Augusto C C Santos, Wagner O Valença, Marcos R Scheide, Claudia C Gatto, Guilherme G C de Carvalho, Pedro M S Costa and 5 more

Abstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Daisy J B LimaDepartment of Physiology and Pharmacology, Federal University of Ceará Fortaleza 60430-270 Ceará Brazil.ORCID https://orcid.org/0000-0002-3474-0678
Renata G AlmeidaInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0003-2896-0487
Guilherme A M JardimInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0002-9882-3085
Breno P A BarbosaDivision of Bioorganic Chemistry, School of Pharmacy, University of Saarland 66123 Saarbruecken Germany.
Augusto C C SantosInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0003-1197-572X
Wagner O ValençaInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0001-8342-6848
Marcos R ScheideDepartment of Chemistry, Federal University of Santa Catarina Florianópolis Santa Catarina 88040-900 Brazil braga.antonio@ufsc.br.ORCID https://orcid.org/0000-0002-1133-9400
Claudia C GattoInstitute of Chemistry, University of Brasilia Brasilia 70904-970 DF Brazil.ORCID https://orcid.org/0000-0002-3736-6861
Guilherme G C de CarvalhoDepartment of Physiology and Pharmacology, Federal University of Ceará Fortaleza 60430-270 Ceará Brazil.
Pedro M S CostaDepartment of Physiology and Pharmacology, Federal University of Ceará Fortaleza 60430-270 Ceará Brazil.ORCID https://orcid.org/0000-0003-3411-2118
Claudia PessoaDepartment of Physiology and Pharmacology, Federal University of Ceará Fortaleza 60430-270 Ceará Brazil.ORCID https://orcid.org/0000-0002-4344-4336
Cynthia L M PereiraInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0002-3799-8092
Claus JacobDivision of Bioorganic Chemistry, School of Pharmacy, University of Saarland 66123 Saarbruecken Germany.ORCID https://orcid.org/0000-0002-6288-7220
Antonio L BragaDepartment of Chemistry, Federal University of Santa Catarina Florianópolis Santa Catarina 88040-900 Brazil braga.antonio@ufsc.br.ORCID https://orcid.org/0000-0001-9903-6764
Eufrânio N da Silva JúniorInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais Belo Horizonte 31270-901 Minas Gerais Brazil eufranio@ufmg.br.ORCID https://orcid.org/0000-0003-1281-5453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the synthesis of 47 new quinone-based derivatives

Identifiers

PMID34778772
PMCPMC8528272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.