ReviewJournal of clinical and translational research2021
Association of dietary total antioxidant capacity with depression, anxiety, and sleep disorders: A systematic review of observational studies.
Review in Journal of clinical and translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Influence of Lycopene Intake on Mental Health: A Systematic Review of Randomized Controlled Trials (RCTs).Nutrients · 2025Pooled it
- Pooled it
- Prediction of antioxidant capacity, age, and sex on sleep impairment in patients with amyotrophic lateral sclerosis.Scientific reports · 2025Trial
- Dietary Carotenoid Intake and Sleep: A Narrative Review of Evidence from Human and In Vivo Animal Studies.Nutrients · 2026Review
- Evaluation of the relationship between sustainable and healthy eating behaviours, phytochemical index, anthropometric measurements, and depression in young adults.Scientific reports · 2026Article
- The effect of fenugreek oral capsule on the sleep quality of primiparous women in the postpartum period: a triple‑blind randomized controlled trial.Maternal health, neonatology and perinatology · 2026Article
- Mindful Eating, Orthorexic Tendency, and Mediterranean Diet Adherence Identify Weight-Related Eating Profiles in Young Adults.Nutrients · 2026Article
- Associations between composite dietary antioxidant index and depressive symptoms among pregnant and postpartum women.BMC pregnancy and childbirth · 2026Article
- Association of seafood consumption with sleep quality according to high sensitivity C-reactive protein levels in Korean adults.The journal of nutrition, health & aging · 2025Article
- Association between oxidative balance score and risk of postpartum depression in Iranian women: a prospective cohort study.Scientific reports · 2025Article
- Article
- Mind-Body Medicine in the Treatment of Depression: A Narrative Review of Efficacy, Safety and Mechanisms.Current psychiatry reports · 2024Review
- Anti-Inflammatory, Antioxidant, and Neuroprotective Effects of Polyphenols-Polyphenols as an Element of Diet Therapy in Depressive Disorders.International journal of molecular sciences · 2023Review
- Higher dietary glycemic load is inversely associated with stress prevalence among Iranian adults.BMC neuroscience · 2022Article
- Role of Nutrition and Diet on Healthy Mental State.Nutrients · 2022Article
- Synergy between psychological impact and biochemical manifestation of stress among the COVID-19 pandemic-affected population.International journal of health sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimWe aimed to systematically review observational studies that evaluated the potential association of the dietary total antioxidant capacity (dTAC) with common mental disorders (depression and anxiety) and sleep disorders.
methodsStudies with an observational design that evaluated the association between the dTAC and common mental disorders and sleep disorders were identified using the PubMed and Scopus databases. The meta-analysis guideline of observational studies in epidemiology and the preferred reporting items for systematic reviews and meta-analysis were used to conduct and report the data of this systematic review.
resultsOf the 439 records, seven studies were included in this review. There was a sample variation of 41-3297 participants. We highlight that five of the studies analyzed were conducted in the Iranian population. Four studies analyzed only women, and three studies were conducted with postmenopausal or climacteric women. Four cross-sectional studies showed inverse associations between the dTAC and depression, anxiety, and sleep disorders in Iranians.
conclusionThe consumption of a diet rich in antioxidants, characterized by high dTAC scores, seems to be inversely associated with depression, anxiety, and sleep disorders. However, further studies with different populations and designs are necessary for a better understand this relationship. RELEVANCE TO PATIENTS: This review assesses the association of the dTAC with common mental disorders (depression and anxiety) with sleep disorders. This will help guide further studies on the relationship between diet and mental disorders and sleep disorders. Knowledge about these relationships is essential for the creation of non-pharmacological practices for the prevention of these disorders.
Indexed as
Identifiers
34778593PMC8580524What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.