ArticleOrthopaedic journal of sports medicine2021
Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction.
Article in Orthopaedic journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02664545 (A Prospective, Randomized, Controlled, Clinical Trial Evaluating the Non-Inferiority of Bridge-Enhanced Anterior Cruciate Ligament Repair), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Randomized, Controlled, Clinical Trial Evaluating the Non-Inferiority of Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) to Anterior Cruciate Ligament Reconstruction With an Autologous Tendon Graft (ACLR)
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Acute anterior cruciate ligament rupture: can repair become an alternative to reconstruction: a meta-analysis of randomized controlled trials and cohort studies.Journal of orthopaedic surgery and research · 2024Pooled it
- Early MRI-based quantitative outcomes are associated with a positive functional performance trajectory from 6 to 24 months post-ACL surgery.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Trial
- Serial Magnetic Resonance Imaging Graft Signal Intensity and its Correlation with Functional Recovery Following Primary Anterior Cruciate Ligament Reconstruction.Journal of orthopaedic case reports · 2026Article
- Comparing Bridge-Enhanced Anterior Cruciate Ligament Repair to Standard Autograft for Anterior Cruciate Ligament Reconstruction: Biomechanical and Clinical Outcomes.Journal of orthopaedic case reports · 2026Article
- Magnetic Resonance Imaging Assessment of Bridge-Enhanced ACL Restoration: An Imaging Atlas of Morphological Features and Healing Trajectories.Orthopaedic journal of sports medicine · 2026Article
- Postcommercialisation outcomes of bridge-enhanced anterior cruciate ligament restoration: The first 100 Bridge registry patients.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Suture-augmented anterior cruciate ligament repair leads to comparable short-term function but a modestly higher re-rupture risk than anterior cruciate ligament reconstruction: A systematic review and meta-analysis.Journal of experimental orthopaedics · 2025Review
- Can repair be an alternative to reconstruction in the management of acute anterior cruciate ligament rupture: A meta-analysis of randomized controlled trials.Journal of experimental orthopaedics · 2025Article
- Indications, Techniques, and Outcomes of Bridge-Enhanced ACL Restoration (BEAR).Current reviews in musculoskeletal medicine · 2025Review
- The Neuroplastic Outcomes from Impaired Sensory Expectations (NOISE) hypothesis: How ACL dysfunction impacts sensory perception and knee stability.Musculoskeletal science & practice · 2025Review
- Evaluating the Importance of Return to Sports and Hamstring Strength in a Discrete Choice Experiment for Anterior Cruciate Ligament Injury.Orthopaedic journal of sports medicine · 2024Article
- Modified Bridge-Enhanced Anterior Cruciate Ligament Repair.Arthroscopy techniques · 2024Article
- Incidence of Osteoarthritis Between ACL Reconstruction With Different Graft Types and Between ACL Reconstruction and Repair: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2024Review
- Nanosurgical and Bioengineering Treatment of Human Anterior Cruciate Ligament Tears with Ultrasound-Guided Injection of Modified Platelet-Rich Plasma Using Human Cell Memory Based on Clinical, Ultrasound, MRI, and Nanoscope Analyses: A Double-Blind Randomized Trial.Journal of clinical medicine · 2024Article
- Comparison of Clinical Outcomes Between Modern Augmented ACL Repair and Autograft ACL Reconstruction: A Systematic Review and Meta-analysis of Studies With Minimum 2-Year Follow-up.Orthopaedic journal of sports medicine · 2024Review
- Augmentation of ACL Autograft Reconstruction With an Amnion Collagen Matrix Wrap and Bone Marrow Aspirate Concentrate: A Pilot Randomized Controlled Trial With 2-Year Follow-up.Orthopaedic journal of sports medicine · 2023Article
- Predicting anterior cruciate ligament failure load with TScientific reports · 2023Article
- Quantitative MRI Biomarkers to Predict Risk of Reinjury Within 2 Years After Bridge-Enhanced ACL Restoration.The American journal of sports medicine · 2023Article
- Bridge enhanced ACL repair vs. ACL reconstruction for ACL tears: A systematic review and meta-analysis of comparative studies.SICOT-J · 2023Article
- Psychological Readiness to Return to Sport at 6 Months Is Higher After Bridge-Enhanced ACL Restoration Than Autograft ACL Reconstruction: Results of a Prospective Randomized Clinical Trial.Orthopaedic journal of sports medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundBridge-enhanced anterior cruciate ligament repair (BEAR) has noninferior patient-reported outcomes when compared with autograft anterior cruciate ligament reconstruction (ACLR) at 2 years. However, the comparison of BEAR and autograft ACLR at earlier time points-including important outcomes such as resolution of knee pain and symptoms, recovery of strength, and return to sport-has not yet been reported. HYPOTHESIS: It was hypothesized that the BEAR group would have higher outcomes on the International Knee Documentation Committee and Knee injury and Osteoarthritis Outcome Score, as well as improved muscle strength, in the early postoperative period. STUDY
designRandomized controlled trial; Level of evidence, 1.
methodsA total of 100 patients aged 13 to 35 years with complete midsubstance anterior cruciate ligament injuries were randomized to receive a suture repair augmented with an extracellular matrix implant (n = 65) or an autograft ACLR (n = 35). Outcomes were assessed at time points up to 2 years postoperatively. Mixed-model repeated-measures analyses were used to compare BEAR and ACLR outcomes. Patients were unblinded after their 2-year visit.
resultsRepeated-measures testing revealed a significant effect of group on the International Knee Documentation Committee Subjective Score (
conclusionPatients undergoing the BEAR procedure had earlier resolution of symptoms and increased satisfaction about their knee function, as well as improved resolution of hamstring muscle strength throughout the 2-year follow-up period. REGISTRATION: NCT02664545 (ClinicalTrials.gov identifier).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.