Evidence map›Paper›PMID 34778460›Full record

ArticleBioMed research international2021

SOCS1 Mediates Berberine-Induced Amelioration of Microglial Activated States in N9 Microglia Exposed to

Qi Guo, Chen Wang, Xiaorong Xue, Bin Hu, He Bao

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Qi GuoDepartment of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.ORCID https://orcid.org/0000-0002-6056-4049
Chen WangDepartment of Pharmacy, The Second Affiliated Hospital of Air Force Medical University, Xi'an 710038, China.
Xiaorong XueDepartment of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
Bin HuDepartment of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710004, China.
He BaoDepartment of Pharmacy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.ORCID https://orcid.org/0000-0002-4609-2815
Xi’an Children’s Hospital · CNAir Force Medical University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attenuating

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesArginaseBerberineCell LineChinaCytokinesHumansInflammationMacrophagesMicrogliaNitric Oxide SynthaseNitric Oxide Synthase Type IISuppressor of Cytokine Signaling 1 ProteinTumor Necrosis Factor-alphaAmyloid beta-PeptidesARG1 protein, humanArginaseBerberineCytokinesNitric Oxide SynthaseNitric Oxide Synthase Type IISOCS1 protein, humanSuppressor of Cytokine Signaling 1 ProteinTumor Necrosis Factor-alpha

Identifiers

PMID34778460
PMCPMC8589517
OpenAlexW3213829364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.