Evidence map›Paper›PMID 34778450›Full record

ArticleBioMed research international2021

The Investigation of Metabonomic Pathways of Serum of Iranian Women with Recurrent Miscarriage Using

Mahbobeh Latifimehr, Ali Asghar Rastegari, Zahra Zamani, Pezhman Fard Esfahani, Leila Nazari

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Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mahbobeh LatifimehrDepartment of Molecular and Cell Biochemistry, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Ali Asghar RastegariDepartment of Molecular and Cell Biochemistry, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Zahra ZamaniDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0003-3701-0854
Pezhman Fard EsfahaniDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Leila NazariDepartment of Obstetrics and Gynecology Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Islamic Azad University, Isfahan · IRPasteur Institute of Iran · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecurrent miscarriage applies to pregnancy loss expulsion of the fetus within the first 24 weeks of pregnancy. This study is aimed at comparatively investigating the sera of women with RM with those who have no record of miscarriages to identify if there were any metabolite and metabolic pathway differences using

methodsSerum samples were collected from women with RM (

resultsThe results of the study revealed that 14 metabolites were different in the patients with RM. Moreover, the pathway analysis showed that taurine and hypotaurine metabolism along with phenylalanine, tyrosine, and tryptophan biosynthesis was significantly different in patients with RM.

conclusionThe present study proposes that any alteration in the above metabolic pathways might lead to metabolic dysfunctions which may result in a higher probability of RM.

Indexed as

Abortion, HabitualAdultDiscriminant AnalysisFemaleHumansIranLeast-Squares AnalysisMagnetic Resonance SpectroscopyMetabolic Networks and PathwaysMetabolomeMetabolomicsPregnancyProton Magnetic Resonance SpectroscopySerum

Identifiers

PMID34778450
PMCPMC8580660
OpenAlexW3210458725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.