Evidence map›Paper›PMID 34778243›Full record

ArticleFrontiers in cell and developmental biology2021

Tet1 Regulates Astrocyte Development and Cognition of Mice Through Modulating GluA1.

Weize Xu, Xicheng Zhang, Feng Liang, Yuhang Cao, Ziyi Li, Wenzheng Qu, Jinyu Zhang, Yanhua Bi, Chongran Sun, Jianmin Zhang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Epigenetic Regulation of Optic Nerve Development, Protection, and Repair.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Weize XuThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xicheng ZhangThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Feng LiangThe Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yuhang CaoThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Ziyi LiDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Wenzheng QuThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jinyu ZhangThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yanhua BiThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Chongran SunThe Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jianmin ZhangThe Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Binggui SunDepartment of Neurobiology and Department of Neurology of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qiang ShuThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xuekun LiThe Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Children's Hospital of Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CNThe University of Texas MD Anderson Cancer Center · USZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tet (Ten eleven translocation) family proteins-mediated 5-hydroxymethylcytosine (5hmC) is highly enriched in the neuronal system, and is involved in diverse biological processes and diseases. However, the function of 5hmC in astrocyte remains completely unknown. In the present study, we show that

Indexed as

astrocytecognitionGluA1neuronal developmentTet1

Identifiers

PMID34778243
PMCPMC8581465
OpenAlexW3210652427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.