ArticleFrontiers in chemistry2021
New Analytical Method for Quantifying Flavoring Chemicals of Potential Respiratory Health Risk Concerns in e-Cigarette Liquids.
Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Characterising 'Spree Bar': an examination of the popularity, marketing and composition of a vaping device with a nicotine analogue across multiple data streams.Tobacco control · 2026Article
- Comparison of Nicotine and Selected Flavoring Contents Between Tobacco-Free and Tobacco-Containing Oral Pouches.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Disposable nicotine vaping products now offer adjustable levels of flavour and coolness.Tobacco control · 2025Article
- Differences in "minty" flavor compound and synthetic cooling agent presence in US-marketed menthol-mint e-liquids and devices between 2019-2023.Research square · 2025Article
- Same brand, same flavour: but not the same product?Tobacco control · 2025Article
- Review
- Biomarkers of Toxicant Exposure among Youth in Canada, England, and the United States Who Vape and/or Smoke Tobacco or Do Neither.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Stability of Flavoring Chemicals in e-Cigarette Liquids: A Naturalistic Product Aging Study over 24 months.ACS omega · 2025Article
- Article
- Chemicals in Cigarette Flavor Capsules From Guatemala and Mexico.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Multi-omic assessment shows dysregulation of pulmonary and systemic immunity to e-cigarette exposure.Respiratory research · 2023Article
- Two Fast GC-MS Methods for the Measurement of Nicotine, Propylene Glycol, Vegetable Glycol, Ethylmaltol, Diacetyl, and Acetylpropionyl in Refill Liquids for E-Cigarettes.Molecules (Basel, Switzerland) · 2023Article
- Changes in product labelling practices and the use of flavouring chemical additives in vaping products after enactment of statewide flavour legislation.Tobacco control · 2022Article
- Removal of mango-flavoured Juul pods created opportunity for adulterated mango Juul-compatible pods with altered chemical constituents.Tobacco control · 2022Article
- Vaping ΔExpert review of clinical pharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous flavoring chemicals are added to e-cigarette liquids to create various flavors. Flavorings provide sensory experience to users and increase product appeal; however, concerns have been raised about their potential inhalation toxicity. Estimating potential health risk of inhaling these chemicals has been challenging since little is known about their actual concentrations in e-cigarette products. To date, a limited number of analytical methods exist to measure the concentrations of flavoring chemicals in e-cigarette products. We have developed an analytical method that accurately and precisely measures the concentrations of 20 flavoring chemicals of potential inhalation risk concerns: 2,3,5-trimethylpyrazine, acetoin, benzaldehyde, benzyl alcohol, butanoic acid, dl-limonene, ethyl maltol, ethyl salicylate, ethyl vanillin, eucalyptol, eugenol, furaneol, isovanillin, l-menthol, maltol, methyl salicylate, pulegone,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.