Evidence map›Paper›PMID 34778203›Full record

ArticleFrontiers in chemistry2021

A Nanofiber Mat With Dual Bioactive Components and a Biomimetic Matrix Structure for Improving Osteogenesis Effect.

Yadi Han, Xiaofeng Shen, Sihao Chen, Xiuhui Wang, Juan Du, Tonghe Zhu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yadi HanFrontier Institute of Medical & Pharmaceutical Science and Technology, College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China.
Xiaofeng ShenDepartment of Orthopedics, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, China.
Sihao ChenFrontier Institute of Medical & Pharmaceutical Science and Technology, College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China.
Xiuhui WangInstitute of Translational Medicine, Shanghai University, Shanghai, China.
Juan DuFrontier Institute of Medical & Pharmaceutical Science and Technology, College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China.
Tonghe ZhuFrontier Institute of Medical & Pharmaceutical Science and Technology, College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, China.
Shanghai University of Engineering Science · CNNanjing University of Chinese Medicine · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The challenge of effectively regenerating bone tissue through tissue engineering technology is that most tissue engineering scaffolds cannot imitate the three-dimensional structure and function of the natural extracellular matrix. Herein, we have prepared the poly(L-lactic acid)-based dual bioactive component reinforced nanofiber mats which were named as poly(L-lactic acid)/bovine serum albumin/nanohydroxyapatite (PLLA/BSA/nHAp) with dual bioactive components by combining homogeneous blending and electrospinning technology. The results showed that these nanofiber mats had sufficient mechanical properties and a porous structure suitable for cell growth and migration. Furthermore, the results of cell experiments

Indexed as

bioactive componentsbone tissue injuremassive bone tissue regenerationnanofiber matrecognition sites

Identifiers

PMID34778203
PMCPMC8586446
OpenAlexW3208513726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.