Evidence map›Paper›PMID 34778097›Full record

ArticleFrontiers in cellular and infection microbiology2021

Changes in the Vaginal Microbiome and Associated Toxicities Following Radiation Therapy for Gynecologic Cancers.

Despina Tsementzi, Rebecca Meador, Tony Eng, Pretesh Patel, Joseph Shelton, Jessica Arluck, Isabelle Scott, Mary Dolan, Namita Khanna, Konstantinos T Konstantinidis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Despina TsementziNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
Rebecca MeadorNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
Tony EngRadiation Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Pretesh PatelRadiation Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Joseph SheltonRadiation Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.
Jessica ArluckDepartment of Obstetrics and Gynecology, Emory University, Atlanta, GA, United States.
Isabelle ScottGrady Memorial Hospital, Atlanta, GA, United States.
Mary DolanDepartment of Obstetrics and Gynecology, Emory University, Atlanta, GA, United States.
Namita KhannaDepartment of Obstetrics and Gynecology, Emory University, Atlanta, GA, United States.
Konstantinos T KonstantinidisSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, United States.
Deborah Watkins BrunerNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
Emory University · USGeorgia Institute of Technology · USGrady Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmenopausal women often suffer from vaginal symptoms associated with atrophic vaginitis. Additionally, gynecologic cancer survivors may live for decades with additional, clinically significant, persistent vaginal toxicities caused by cancer therapies, including pain, dyspareunia, and sexual dysfunction. The vaginal microbiome (VM) has been previously linked with vaginal symptoms related to menopause (

Indexed as

DyspareuniaMicrobiotaNeoplasmsFemaleHumansLactobacillusMenopauseVaginagynecologic cancerlongitudinal dynamicspostmenopausal womenradiation toxicitiesvaginal microbial communityvaginal microbiome

Identifiers

PMID34778097
PMCPMC8580013
OpenAlexW3209607649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.