Evidence map›Paper›PMID 34777991›Full record

ReviewJournal of clinical orthopaedics and trauma2021

Carbon fibre reinforced PEEK versus traditional metallic implants for orthopaedic trauma surgery: A systematic review.

Kanthan Theivendran, Faizan Arshad, Umar-Khetaab Hanif, Aleksi Reito, Xavier Griffin, Clary J Foote

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical orthopaedics and trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Carbon-fibre plates for traumatic and (impending) pathological fracture fixation: Where do we stand? A systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023
    Pooled it
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  8. Patient perspective on the use of carbon fibre plates for extremity fracture fixation.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Kanthan TheivendranSandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
Faizan ArshadSandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
Umar-Khetaab HanifSandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
Aleksi ReitoTampere University Hospital (TAUH), Tampere, Finland.
Xavier GriffinDivision of Trauma & Orthopaedic Surgery, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.
Clary J FooteMcMaster University, Hamilton, Canada.
Sandwell & West Birmingham Hospitals NHS Trust · GBAston University · GBMcMaster University · CAQueen Mary University of London · GBTampere University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is no literature review comparing outcomes of fixation using carbon-fibre-reinforced polyetheretherketone (CFR PEEK) compared to metal implants used in orthopaedic extremity trauma surgery. A systematic review was performed to compare CFR PEEK to metal implants for clinically-important fracture outcomes.

methodsA search of the online databases of PubMed/Medline, EMBASE and Cochrane Database was conducted. A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A meta-analyses was performed for functional outcomes in proximal humerus fractures converting the score differences to standard mean difference units. GRADE approach was used to determine the level of certainty of the estimates.

resultsTwo prospective randomised controlled trials and seven comparative observational studies with a total of 431 patients were included. Of the nine studies included, four compared the use of CFR PEEK against metal plates in proximal humerus fractures. Aggregated functional scores across the proximal humerus studies, there was a small signal of better improvement with CFR PEEK (SMD 0.22, 95% CI -0.03 to 0.47, p = 0.08, low certainty). Greater odds of adverse events occurred in the metal group (OR 2.34, 95% CI 0.73 to 7.55, p = 0.15, low certainty).

conclusionsLow to very low certainty evidence suggests a small improvement in functional recovery with CFR PEEK in proximal humerus fractures. This may be mediated through a small reduction in major adverse events related to fracture healing and stability. There is currently insufficient evidence to support the widespread use of CFR PEEK implants in fracture fixation. LEVEL OF EVIDENCE: Level IV.

Indexed as

BiomaterialsCarbon-fibre-reinforced polyetheretherketoneCFR PEEKEvidence-based orthopedicsFixationFractureMeta-analysisSystematic reviewTrauma outcomes

Identifiers

PMID34777991
PMCPMC8577430
OpenAlexW3208646327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.