Evidence map›Paper›PMID 34777889›Full record

ArticleCase reports in psychiatry2021

Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam.

Antti Mustonen, Juhani Leijala, Johanna Aronranta, Antero Lassila, Mauri Aalto, Janne Koskimäki

Abstract readCase Reports
In one paragraph

Article in Case reports in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antti MustonenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0002-3259-2122
Juhani LeijalaDepartment of Psychiatry, Central Hospital of Southern Ostrobothnia, Hanneksenrinne 7, FI-60220 Seinäjoki, Finland.ORCID https://orcid.org/0000-0003-1542-3746
Johanna AronrantaDepartment of Psychiatry, Central Hospital of Southern Ostrobothnia, Hanneksenrinne 7, FI-60220 Seinäjoki, Finland.
Antero LassilaDepartment of Psychiatry, Central Hospital of Southern Ostrobothnia, Hanneksenrinne 7, FI-60220 Seinäjoki, Finland.
Mauri AaltoFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0003-3424-3767
Janne KoskimäkiDepartment of Psychiatry, Central Hospital of Southern Ostrobothnia, Hanneksenrinne 7, FI-60220 Seinäjoki, Finland.ORCID https://orcid.org/0000-0002-2311-6327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases.

Identifiers

PMID34777889
PMCPMC8589494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.