ReviewArrhythmia & electrophysiology review2021
Physiology and Practicality of Left Ventricular Septal Pacing.
Review in Arrhythmia & electrophysiology review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Conduction system pacing for cardiac resynchronization therapy: a systematic review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Pooled it
- Permanent LEft ventricular septAl Pacing vs. right ventricular pacing in patients with atrioventricular conduction disorders-a randomized trial: rationale and design of the LEAP trial.European heart journal open · 2026Article
- Left bundle branch pacing is a superior pacing strategy compared to left ventricular septal pacing: insights from the pooled clinical evidence.Frontiers in physiology · 2026Review
- Efficacy and safety of left bundle branch pacing compared with left ventricular septal pacing: A systematic review and meta-analysis.Heart rhythm O2 · 2025Article
- Left bundle branch pacing vs ventricular septal pacing for cardiac resynchronization therapy.Heart rhythm O2 · 2024Article
- Comparison of methods for delivering cardiac resynchronization therapy: an acute electrical and haemodynamic within-patient comparison of left bundle branch area, His bundle, and biventricular pacing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Conduction system pacing for cardiac resynchronization therapy: State of the art, current controversies, and future perspectives.Frontiers in physiology · 2023Review
- An Electrocardiographic Characterization of Left Bundle Branch Area Pacing-Induced Right Ventricular Activation Delay: A Comparison With Native Right Bundle Branch Block.Frontiers in cardiovascular medicine · 2022Article
- Electro-energetics of Biventricular, Septal and Conduction System Pacing.Arrhythmia & electrophysiology review · 2021Review
- Simple is Complicated.Arrhythmia & electrophysiology review · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left ventricular septal pacing (LVSP) and left bundle branch pacing (LBBP) have been introduced to maintain or correct interventricular and intraventricular (dys)synchrony. LVSP is hypothesised to produce a fairly physiological sequence of activation, since in the left ventricle (LV) the working myocardium is activated first at the LV endocardium in the low septal and anterior free-wall regions. Animal studies as well as patient studies have demonstrated that LV function is maintained during LVSP at levels comparable to sinus rhythm with normal conduction. Left ventricular activation is more synchronous during LBBP than LVSP, but LBBP produces a higher level of intraventricular dyssynchrony compared to LVSP. While LVSP is fairly straightforward to perform, targeting the left bundle branch area may be more challenging. Long-term effects of LVSP and LBBP are yet to be determined. This review focuses on the physiology and practicality of LVSP and provides a guide for permanent LVSP implantation.
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Registered trials
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