Evidence map›Paper›PMID 34777768›Full record

ArticleChemical science2021

Stress response decay with aging visualized using a dual-channel logic-based fluorescent probe.

Jingye Tian, Donglei Shi, Yanhui Zhang, Xiaokang Li, Xinming Li, Hao Teng, Tony D James, Jian Li, Yuan Guo

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jingye TianKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 China guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0002-8114-8159
Donglei ShiState Key Laboratory of Bioreactor Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy, East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China jianli@ecust.edu.cn.ORCID https://orcid.org/0000-0002-3934-5650
Yanhui ZhangKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 China guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0002-6597-3300
Xiaokang LiState Key Laboratory of Bioreactor Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy, East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China jianli@ecust.edu.cn.ORCID https://orcid.org/0000-0001-8154-551X
Xinming LiState Key Laboratory of Bioreactor Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy, East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China jianli@ecust.edu.cn.ORCID https://orcid.org/0000-0002-1304-1499
Hao TengKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 China guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0002-6043-3962
Tony D JamesDepartment of Chemistry, University of Bath Bath BA2 7AY UK.ORCID https://orcid.org/0000-0002-4095-2191
Jian LiState Key Laboratory of Bioreactor Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy, East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China jianli@ecust.edu.cn.ORCID https://orcid.org/0000-0002-7521-8798
Yuan GuoKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University Xi'an 710127 China guoyuan@nwu.edu.cn.ORCID https://orcid.org/0000-0003-2081-7264
East China University of Science and Technology · CNMinistry of Education of the People's Republic of China · CNUniversity of Bath · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing aging for preventative intervention generally relies on the tracking of aging biomarkers in the resting state. However, the static marker levels are insufficient to fully evaluate aging, particularly given that the stress response capacity (SRC) decay is currently viewed as a critical feature of aging. Therefore, we have developed a dual-channel fluorescent probe

Identifiers

PMID34777768
PMCPMC8528035
OpenAlexW3201621719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.