Evidence map›Paper›PMID 34777704›Full record

ReviewMalawi medical journal : the journal of Medical Association of Malawi2021

Potential of Malawi's medicinal plants in Covid-19 disease management: A review.

Ibrahim Chikowe, Andrew G Mtewa, David Tembo, Dallas Smith, Edna Ibrahim, Bonface Mwamatope, Justin Nkhungulu, Peter Kumpalume, Alfred Maroyi

Open access · diamondAbstract readReview
In one paragraph

Review in Malawi medical journal : the journal of Medical Association of Malawi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ibrahim ChikowePharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences.
Andrew G MtewaChemistry Section, Malawi Institute of Technology, Malawi University of Science and Technology, Thyolo, Malawi.
David TemboThe Polytechnic, University of Malawi, Blantyre, Malawi/Malawi University of Business and Applied Sciences.
Dallas SmithPharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences.
Edna IbrahimThe Polytechnic, University of Malawi, Blantyre, Malawi/Malawi University of Business and Applied Sciences.
Bonface MwamatopeUniversity of Livingstonia, Rumphi, Malawi.
Justin NkhunguluPharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences.
Peter KumpalumePharmacy Department, College of Medicine, University of Malawi, Blantyre, Malawi/Kamuzu University of Health Sciences.
Alfred MaroyiUniversity of Fort Hare, Alice, South Africa.
Kamuzu University of Health SciencesUniversity of Malawi · MWMalawi University of Science and Technology · MWUniversity of Fort Hare · ZAUniversity of Livingstonia · MW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered an international pandemic that has led to significant public health problems. To date, limited evidence exists to suggest that drugs are effective against the disease. As possible treatments are being investigated, herbal medicines have shown potential for producing novel antiviral agents for the COVID-19 disease. Aim: This review explored the potential of Malawi's traditional medicinal plants for the management of COVID-19. Methods: The authors searched on PubMed and Google scholar for medicinal plants that are used in Malawi and published in openly available peer reviewed journals. Plants linked with antiviral treatment, anti-COVID-19 activity or COVID-19 symptoms management were targeted. These included activity against pneumonia, inflammation, cough, difficulty in breathing, pain/aches, fever, diarrhoea, rheumatism, fatigue, asthma, immunocompromised and cardiovascular diseases. Results: 11 studies were found with 306 plant species. 127 plant species had at least one COVID-19 related pharmacological activity. Of these plant species, the number of herbal entities used for each indication was: pain/aches (87), fever (2), pneumonia (9), breathing/asthma problems (5), coughing (11), diarrhoea (1), immunosuppression (8), blood issues (10), fatigue (2), heart problems (11), inflammation (8), rheumatism (10) and viral diseases (12). Thirty (30) species were used for more than one disease and Conclusion: Medicinal plants are a promising source of compounds that can be used for drug development of COVID-19 related diseases. This review highlights potential targets for the World Health Organization and other research entities to explore in order to assist in controlling the pandemic.

Indexed as

COVID-19Plants, MedicinalAntiviral AgentsHumansMalawiPhytochemicalsSARS-CoV-2Antiviral AgentsPhytochemicalscorona virusdrug developmentherbal productsscreeningtraditional medicine

Identifiers

PMID34777704
PMCPMC8560350
OpenAlexW3192314007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.