Evidence map›Paper›PMID 34777683›Full record

ArticleOxidative medicine and cellular longevity2021

Trilobatin Alleviates Cognitive Deficits and Pathologies in an Alzheimer's Disease Mouse Model.

Jiuyang Ding, Jian Huang, Dan Yin, Ting Liu, Zheng Ren, Shanshan Hu, Yuanliang Ye, Cuiyun Le, Na Zhao, Hongmei Zhou and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Exploring the Impact of 3-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
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  9. Article
  10. Frontiers in neuroscience · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jiuyang DingSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.ORCID https://orcid.org/0000-0001-9089-1756
Jian HuangSchool of Forensic Medicine, Southern Medical University, Guangzhou 510515, China.
Dan YinLaboratory of Electron Microscopy, School of Basic Medicine, Guizhou Medical University, Guiyang 550004, China.
Ting LiuState Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province, Guizhou Medical University, Guiyang 550004, China.ORCID https://orcid.org/0000-0002-5824-3975
Zheng RenSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.
Shanshan HuGood Clinical Practice Center, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, China.
Yuanliang YeDepartment of Neurosurgery, Liuzhou People's Hospital, Liuzhou, China.
Cuiyun LeSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.
Na ZhaoSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.
Hongmei ZhouSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.
Zhu LiSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.
Xiaolan QiKey Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, China.
Jiang HuangSchool of Forensic Medicine, Guizhou Medical University, Guiyang 550004, China.ORCID https://orcid.org/0000-0002-6821-3665
Guiyang Medical University · CNLiuzhou General Hospital · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disease nowadays that causes memory impairments. It is characterized by extracellular aggregates of amyloid-beta (A

Indexed as

Alzheimer DiseaseAnimalsCognitive DysfunctionFlavonoidsHumansMaleMemory DisordersMiceMice, Inbred C57BLMice, TransgenicNeuroinflammatory DiseasesNeuroprotective AgentsPolyphenolstau ProteinsFlavonoidsNeuroprotective AgentsPolyphenolstau Proteinstrilobatin

Identifiers

PMID34777683
PMCPMC8589506
OpenAlexW3214294467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.