Evidence map›Paper›PMID 34777519›Full record

ArticleIranian journal of veterinary research2021

Effects of citral on serum antioxidant status and liver genes expressions of

M Khosravi Bakhtiari, H Sharifiyazdi, S Nazifi, M Ghaemi, M Hadadipour Zarandi

Open access · greenAbstract read
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Article in Iranian journal of veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M Khosravi BakhtiariResident of Clinical Pathology, Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
H SharifiyazdiDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
S NazifiDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
M GhaemiDepartment of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
M Hadadipour ZarandiResident of Clinical Pathology, Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Shiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCitral (C

aimsThis study aimed to investigate the ameliorative effects of citral on selected oxidative parameters and the gene expression of

methodsForty rats were divided into four groups at random: control (C), control citral (CC), and two STZ-induced diabetic groups (diabetic (D) and citral diabetic (CD)). After diabetes confirmation (day 7), gavage treatment with citral (300 mg/kg body weight (BW)) was started in the CD and CC groups and continued for two weeks.

resultsOn day 21 of the study, following treatment with citral for 14 days, the serum levels of total antioxidant capacity (TAC), and PON1 in the CD group were significantly increased compared to those in the D group (P<0.05). While treatment with citral caused a significant decrease in the Malondialdehyde (MDA), and eNOS in the CD group compared to those of the D group (P<0.001). The expression rate of liver

conclusionThis study showed positive effects of citral on serum antioxidant status and liver gene expression of

Indexed as

CitralDiabetesGene expressionNitric oxide synthaseParaoxonase 1

Identifiers

PMID34777519
PMCPMC8573404
OpenAlexW3213115962

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.