Evidence map›Paper›PMID 34777384›Full record

ArticleFrontiers in immunology2021

Self-Organizing Maps for Cellular

Edwin Yuan, Magdalena Matusiak, Korsuk Sirinukunwattana, Sushama Varma, Łukasz Kidziński, Robert West

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Edwin YuanDepartment of Applied Physics, Stanford University, Stanford, CA, United States.
Magdalena MatusiakDepartment of Pathology, Stanford University, Stanford, CA, United States.
Korsuk SirinukunwattanaInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.
Sushama VarmaDepartment of Pathology, Stanford University, Stanford, CA, United States.
Łukasz KidzińskiDepartment of Bioengineering, Stanford University, Stanford, CA, United States.
Robert WestDepartment of Pathology, Stanford University, Stanford, CA, United States.
Stanford University · USNational Health Service · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular composition and structural organization of cells in the tissue determine effective antitumor response and can predict patient outcome and therapy response. Here we present Seg-SOM, a method for dimensionality reduction of cell morphology in H&E-stained tissue images. Seg-SOM resolves cellular tissue heterogeneity and reveals complex tissue architecture. We leverage a self-organizing map (SOM) artificial neural network to group cells based on morphological features like shape and size. Seg-SOM allows for cell segmentation, systematic classification, and

Indexed as

AlgorithmsBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingCluster AnalysisEpithelial CellsFemaleFibroblastsHumansLymphocytesNeural Networks, ComputerStaining and Labelingcell subtype classificatione-pathologyin silico stainingsegmentationself-organization

Identifiers

PMID34777384
PMCPMC8588845
OpenAlexW3210277661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.