ArticleFrontiers in microbiology2021
Machine Learning Uncovers a Data-Driven Transcriptional Regulatory Network for the Crenarchaeal Thermoacidophile
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis Driven Strain Design for Mitigating Oxidative Stresses Important in Biomanufacturing.ACS synthetic biology · 2024Pooled it
- Review
- Community composition of arbuscular mycorrhizal fungi in Ontario tallgrass prairies of differing disturbance histories.Mycorrhiza · 2026Article
- Revealing transcriptomic responses inmSystems · 2026Article
- iModulonDB 2.0: dynamic tools to facilitate knowledge-mining and user-enabled analyses of curated transcriptomic datasets.Nucleic acids research · 2025Article
- Article
- AI-driven parametrization of Michaelis-Menten maximal velocity: Advancing in silico new approach methodologies (NAMs).NAM journal · 2025Article
- iModulonMiner and PyModulon: Software for unsupervised mining of gene expression compendia.PLoS computational biology · 2024Article
- Machine learning reveals the transcriptional regulatory network and circadian dynamics ofProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Proteome allocation is linked to transcriptional regulation through a modularized transcriptome.Nature communications · 2024Article
- Article
- Impact of nutrient excess on physiology and metabolism ofFrontiers in microbiology · 2024Article
- Molecular insights and omics-based understanding of plant-microbe interactions under drought stress.World journal of microbiology & biotechnology · 2023Review
- A multi-scale expression and regulation knowledge base for Escherichia coli.Nucleic acids research · 2023Article
- Laboratory evolution, transcriptomics, and modeling reveal mechanisms of paraquat tolerance.Cell reports · 2023Article
- Independent Component Analysis Reveals the Transcriptional Regulatory Modules inInternational journal of molecular sciences · 2023Article
- Proteome allocation is linked to transcriptional regulation through a modularized transcriptome.bioRxiv : the preprint server for biology · 2023Article
- Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeonFrontiers in microbiology · 2023Article
- Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic cellular responses to environmental constraints are coordinated by the transcriptional regulatory network (TRN), which modulates gene expression. This network controls most fundamental cellular responses, including metabolism, motility, and stress responses. Here, we apply independent component analysis, an unsupervised machine learning approach, to 95 high-quality
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Registered trials
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