Evidence map›Paper›PMID 34777062›Full record

ArticleFrontiers in psychiatry2021

EEG Microstates and Its Relationship With Clinical Symptoms in Patients With Schizophrenia.

Qiaoling Sun, Jiansong Zhou, Huijuan Guo, Ningzhi Gou, Ruoheng Lin, Ying Huang, Weilong Guo, Xiaoping Wang

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiaoling SunDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Jiansong ZhouDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Huijuan GuoDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Ningzhi GouDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Ruoheng LinDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Ying HuangDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Weilong GuoDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Xiaoping WangDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is a complex and devastating disorder with unclear pathogenesis. Electroencephalogram (EEG) microstates have been suggested as a potential endophenotype for this disorder. However, no clear dynamic pattern of microstates has been found. This study aims to identify the dynamics of EEG microstates in schizophrenia and to test whether schizophrenia patients with altered clinical symptoms severity showed different microstates abnormalities compared with healthy controls. Resting-state EEG data in 46 individuals who met the ICD-10 diagnostic criteria for schizophrenia and 39 healthy controls was recorded. The patients with schizophrenia were divided into subgroups based on the level of their negative or positive symptoms assessed using the Positive and Negative Syndrome Scale. Microstate parameters (contribution, occurrence, and duration) of four prototypical microstate classes (A-D) were investigated. Compared with healthy controls, individuals with schizophrenia showed increased duration and contribution of microstate class C, decreased contribution and occurrence of microstate class B. Different microstate patterns were found between subgroups and healthy controls. Results in this study support the consistent observation of abnormal EEG microstates patterns in patients with schizophrenia and highlight the necessity to divide subjects into subgroups according to their clinical symptoms.

Indexed as

clinical symptomselectroencephalogram (EEG)microstatesresting-stateschizophrenia

Identifiers

PMID34777062
PMCPMC8581189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.