Evidence map›Paper›PMID 34777021›Full record

ArticleFrontiers in physiology2021

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology.

Karoline Horgmo Jæger, Andrew G Edwards, Wayne R Giles, Aslak Tveito

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

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  4. Sometimes extracellular recordings fail for good reasons.NPJ systems biology and applications · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Karoline Horgmo JægerSimula Research Laboratory, Lysaker, Norway.
Andrew G EdwardsSimula Research Laboratory, Lysaker, Norway.
Wayne R GilesSimula Research Laboratory, Lysaker, Norway.
Aslak TveitoSimula Research Laboratory, Lysaker, Norway.
Simula Research Laboratory · NOUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational modeling has contributed significantly to present understanding of cardiac electrophysiology including cardiac conduction, excitation-contraction coupling, and the effects and side-effects of drugs. However, the accuracy of

Indexed as

action potential propagationcardiac diseasecardiac modelingcell based modelcomputational electrophysiologycomputational modelingconduction abnormalitiesEMI model

Identifiers

PMID34777021
PMCPMC8578869
OpenAlexW3211009370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.