SynthesisFrontiers in aging neuroscience2021
Transcranial Direct Current Stimulation for Parkinson's Disease: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- The different stimulation durations of transcranial direct current stimulation for Parkinson's disease: a systematic review and network meta-analysis.Frontiers in aging neuroscience · 2026Pooled it
- Efficacy of transcranial direct current stimulation on cognitive function in patients with Parkinson's disease: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2025Pooled it
- Effects of transcranial direct current stimulation on non-motor functions in individuals with Parkinson's disease: a systematic review and meta-analysis.Frontiers in neuroscience · 2025Pooled it
- Effects of transcranial direct current stimulation alone and in combination with rehabilitation therapies on gait and balance among individuals with Parkinson's disease: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Acute Effect of Transcranial Direct Current Stimulation in Pelvic Floor Muscle Function in Young Healthy Women: Initial Findings of a Randomized Controlled Trial.International urogynecology journal · 2024Trial
- Transcranial direct current stimulation enhances motor learning in Parkinson's disease: a randomized controlled trial.Journal of neurology · 2023Trial
- Depression in neurodegenerative disease: neurobiological mechanisms and emerging treatments.Molecular psychiatry · 2026Review
- Noninvasive Brain Stimulation for Parkinson's Disease: Therapeutic Applications and Clinical Perspectives.Journal of movement disorders · 2026Article
- Non-invasive neuromodulation techniques for cognitive impairment intervention.American journal of translational research · 2026Review
- Study Protocol: Investigating the Effects of Transcranial Pulse Stimulation in Parkinson's Disease.Bioengineering (Basel, Switzerland) · 2025Article
- Biofeedback for Motor and Cognitive Rehabilitation in Parkinson's Disease: A Comprehensive Review of Non-Invasive Interventions.Brain sciences · 2025Review
- Efficacy of brain stimulation therapies across psychiatric, movement, and cognitive disorders: an umbrella review synthesizing meta-analyses of randomized controlled trials.EClinicalMedicine · 2025Article
- Targeting the parietal memory network with tDCS in MCI: study protocol for a randomized controlled trial.Frontiers in human neuroscience · 2025Article
- The safety and feasibility of transcranial direct current stimulation combined with conservative treatment for patients with cervicogenic headaches: A double-blinded randomized control study protocol.Contemporary clinical trials communications · 2024Article
- Transcranial direct current stimulation for Parkinson's disease: systematic review and meta-analysis of motor and cognitive effects.NPJ Parkinson's disease · 2024Article
- Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Review
- The Role of Non-Invasive Brain Modulation in Identifying Disease Biomarkers for Diagnostic and Therapeutic Purposes in Parkinsonism.Brain sciences · 2024Review
- Treatment of apathy in Parkinson's disease: A bayesian network meta-analysis of randomised controlled trials.Heliyon · 2024Article
- Article
- Noninvasive Neuromodulation in Parkinson's Disease: Insights from Animal Models.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParkinson's disease is a common neurodegenerative disorder with motor and non-motor symptoms. Recently, as adjuvant therapy, transcranial direct current stimulation (tDCS) has been shown to improve the motor and non-motor function of patients with Parkinson's disease (PD). This systematic review aimed to evaluate the existing evidence for the efficacy of tDCS for PD. We included English databases (PubMed, the Cochrane Library, Embase, and Web of Science) and Chinese databases [Wanfang database, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), and China Biology Medicine (CBM)] without restricting the year of publication. Twenty-one tDCS studies, with a total of 736 participants, were included in the analysis. Two independent researchers extracted the data and characteristics of each study. There was a significant pooled effect size (-1.29; 95% CI = -1.60, -0.98;
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.