Evidence map›Paper›PMID 34776855›Full record

ArticleFrontiers in neuroscience2021

Efficacy Evaluation of Neurofeedback-Based Anxiety Relief.

Chao Chen, Xiaolin Xiao, Abdelkader Nasreddine Belkacem, Lin Lu, Xin Wang, Weibo Yi, Penghai Li, Changming Wang, Sha Sha, Xixi Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  8. Closed-Loop Systems and Real-Time Neurofeedback in Mindfulness Meditation Research.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Chao ChenAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Xiaolin XiaoAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Abdelkader Nasreddine BelkacemDepartment of Computer and Network Engineering, College of Information Technology, United Arab Emirates University, Al Ain, United Arab Emirates.
Lin LuZhonghuan Information College, Tianjin University of Technology, Tianjin, China.
Xin WangKey Laboratory of Complex System Control Theory and Application, Tianjin University of Technology, Tianjin, China.
Weibo YiBeijing Machine and Equipment Institute, Beijing, China.
Penghai LiKey Laboratory of Complex System Control Theory and Application, Tianjin University of Technology, Tianjin, China.
Changming WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Sha ShaBeijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Xixi ZhaoBeijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Dong MingAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Beijing Anding Hospital · CNTianjin University of Technology · CNTianjin University · CNTianjin Medical University · CNUnited Arab Emirates University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety disorder is a mental illness that involves extreme fear or worry, which can alter the balance of chemicals in the brain. This change and evaluation of anxiety state are accompanied by a comprehensive treatment procedure. It is well-known that the treatment of anxiety is chiefly based on psychotherapy and drug therapy, and there is no objective standard evaluation. In this paper, the proposed method focuses on examining neural changes to explore the effect of mindfulness regulation in accordance with neurofeedback in patients with anxiety. We designed a closed neurofeedback experiment that includes three stages to adjust the psychological state of the subjects. A total of 34 subjects, 17 with anxiety disorder and 17 healthy, participated in this experiment. Through the three stages of the experiment, electroencephalography (EEG) resting state signal and mindfulness-based EEG signal were recorded. Power spectral density was selected as the evaluation index through the regulation of neurofeedback mindfulness, and repeated analysis of variance (ANOVA) method was used for statistical analysis. The findings of this study reveal that the proposed method has a positive effect on both types of subjects. After mindfulness adjustment, the power map exhibited an upward trend. The increase in the average power of gamma wave indicates the relief of anxiety. The enhancement of the wave power represents an improvement in the subjects' mindfulness ability. At the same time, the results of ANOVA showed that

Indexed as

anxiety assessmentanxiety disorderEEG signalefficacy evaluationneurofeedback

Identifiers

PMID34776855
PMCPMC8581142
OpenAlexW3211047537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.