ArticleFrontiers in neuroscience2021
A Time-Course-Based Estimation of the Human Medial Olivocochlear Reflex Function Using Clicks.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Rapid Characterization of Middle-Ear Muscle Reflexes Using Swept Elicitors.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- The Effects of Broadband Elicitor Duration on Transient-Evoked Otoacoustic Emissions and a Psychoacoustic Measure of Gain Reduction.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Relationships between the expectations based on the regularity of preceding sound sequences and the medial olivocochlear reflex.PloS one · 2024Article
- Speech Perception in Noise and Medial Olivocochlear Reflex: Effects of Age, Speech Stimulus, and Response-Related Variables.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Auditory brainstem mechanisms likely compensate for self-imposed peripheral inhibition.Scientific reports · 2023Article
- The effects of broadband elicitor duration on a psychoacoustic measure of cochlear gain reduction.The Journal of the Acoustical Society of America · 2023Article
- The hunt for hidden hearing loss in humans: From preclinical studies to effective interventions.Frontiers in neuroscience · 2022Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The auditory efferent system, especially the medial olivocochlear reflex (MOCR), is implicated in both typical auditory processing and in auditory disorders in animal models. Despite the significant strides in both basic and translational research on the MOCR, its clinical applicability remains under-utilized in humans due to the lack of a recommended clinical method. Conventional tests employ broadband noise in one ear while monitoring change in otoacoustic emissions (OAEs) in the other ear to index efferent activity. These methods, (1) can only assay the contralateral MOCR pathway and (2) are unable to extract the kinetics of the reflexes. We have developed a method that re-purposes the same OAE-evoking click-train to also concurrently elicit bilateral MOCR activity. Data from click-train presentations at 80 dB peSPL at 62.5 Hz in 13 young normal-hearing adults demonstrate the feasibility of our method. Mean MOCR magnitude (1.7 dB) and activation time-constant (0.2 s) are consistent with prior MOCR reports. The data also suggest several advantages of this method including, (1) the ability to monitor MEMR, (2) obtain both magnitude and kinetics (time constants) of the MOCR, (3) visual and statistical confirmation of MOCR activation.
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