Evidence map›Paper›PMID 34776827›Full record

ArticleFood & nutrition research2021

Soo-Im Choi, SoHyeon You, SukJin Kim, GaYeong Won, Chang-Ho Kang, Gun-Hee Kim

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Improving Lipid Profiles ThroughFoods (Basel, Switzerland) · 2026
    Review
  6. Review
  7. Article
  8. Nutrients · 2025
    Review
  9. Nutrients · 2025
    Article
  10. Probiotic, Postbiotic, and Paraprobiotic Effects ofFoods (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. TheFrontiers in microbiology · 2023
    Review
  16. Review
  17. Microorganisms · 2022
    Article
  18. Review
  19. Article
  20. Microorganisms · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Soo-Im ChoiDepartment of Health Functional Materials, Duksung Women's University, Seoul, Republic of Korea.
SoHyeon YouDepartment of Health Functional Materials, Duksung Women's University, Seoul, Republic of Korea.
SukJin KimDepartment of Health Functional Materials, Duksung Women's University, Seoul, Republic of Korea.
GaYeong WonDepartment of Health Functional Materials, Duksung Women's University, Seoul, Republic of Korea.
Chang-Ho KangR&D Center, MEDIOGEN Co., Ltd., Seoul, Republic of Korea.
Gun-Hee KimDepartment of Health Functional Materials, Duksung Women's University, Seoul, Republic of Korea.
Duksung Women's University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive consumption of dietary fat is closely related to obesity, diabetes, insulin resistance, cardiovascular disease, hypertension, and non-alcoholic fatty liver disease. Recently, probiotics have been highly proposed as biotherapeutic to treat and prevent diseases. Previously, there are studies that demonstrated the beneficial effects of probiotics against metabolic disorders, including obesity and diabetes.

objectiveWe investigated the anti-obesity effect and mechanism of action of four human-derived lactic acid bacterial (LAB) strains (

designObesity was induced in mice over 8 weeks, with a 60% HFD. The four human-derived LAB strains (2 × 10

resultsAdministration of these LAB strains resulted in decreased body weight, liver and AT weights, and glucose tolerance. Serum biochemistry profiles, including triglyceride (TG), total cholesterol, low-density lipoprotein cholesterol, and leptin, pro-inflammatory cytokines, improved. Hepatic steatosis and TG levels in liver tissue were significantly reduced. In addition, the size of adipocytes in epididymal tissue was significantly reduced. In epididymal tissues,

conclusionWe suggest that

Indexed as

anti-obesityhigh-fat dietLimosilactobacillus reuteri MG5149probioticsWeissella cibaria MG5285

Identifiers

PMID34776827
PMCPMC8559444
OpenAlexW3209276674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.