Evidence map›Paper›PMID 34776793›Full record

ArticleCurrent infectious disease reports2021

Recent Updates in Antimicrobial Stewardship in Outpatient Parenteral Antimicrobial Therapy.

Monica V Mahoney, Lindsey M Childs-Kean, Parisa Khan, Christina G Rivera, Ryan W Stevens, Keenan L Ryan

Open access · bronzeAbstract read
In one paragraph

Article in Current infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 32 citations in OpenAlex.

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  15. Review
  16. Outpatient parenteral antimicrobial therapy in pediatrics: the role of antimicrobial stewardship.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  17. The OPAT opportunity for beta-lactam individualization.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  18. Review
  19. Article
  20. Implementation of a Collaborated Antimicrobial Stewardship Program and Outpatient Parenteral Antimicrobial Therapy (OPAT) Unit-driven Monoclonal Antibody Therapy Program for COVID-19 at an NYC Hospital.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Monica V MahoneyBeth Israel Deaconess Medical Center, Boston, MA USA.ORCID 0000-0002-5071-2159
Lindsey M Childs-KeanDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL USA.
Parisa KhanMichael E. DeBakey VA Medical Center, Houston, TX USA.
Christina G RiveraDepartment of Pharmacy, Mayo Clinic, Rochester, MN USA.
Ryan W StevensDepartment of Pharmacy, Mayo Clinic, Rochester, MN USA.
Keenan L RyanInpatient Pharmacy Department, University of New Mexico Hospital, Albuquerque, NM USA.
Mayo Clinic · USAmerican Association of Colleges of Pharmacy · USBeth Israel Deaconess Medical Center · USMichael E. DeBakey VA Medical Center · USUniversity of New Mexico Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAntimicrobial stewardship within acute care is common and has been expanding to outpatient areas. Some inpatient antimicrobial stewardship tactics apply to outpatient parenteral antimicrobial therapy (OPAT) and complex outpatient antimicrobial therapy (COpAT) management, but differences do exist. RECENT

findingsOPAT/COpAT is a growing area of practice and research with its own unique considerations for antimicrobial stewardship. Potential ideas for antimicrobial stewardship in the OPAT/COpAT setting include redesigning the regimen to COpAT instead of OPAT, ensuring the use of the shortest effective duration of antimicrobial therapy; using antimicrobials dosed less frequently, such as long-acting glycopeptides; optimizing antimicrobial susceptibility testing reporting for common OPAT/COpAT drugs; and establishing routine laboratory and safety monitoring. Future consensus is needed to determine validated OPAT program metrics and outcomes. SUMMARY: As more focus is placed on outpatient antimicrobial stewardship, clinicians practicing in OPAT should publish more data regarding OPAT program methods and outcomes as they relate to antimicrobial stewardship. These can involve patient clinical outcomes, OPAT readmission rates, OPAT therapy completion, and central line-related complications.

Indexed as

Antimicrobial stewardshipHome careOPATOutpatient parenteral antimicrobial therapy

Identifiers

PMID34776793
PMCPMC8577634
OpenAlexW3214382182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.