Evidence map›Paper›PMID 34776498›Full record

ArticleJournal of epidemiology2023

Measures of Early-life Behavior and Later Psychopathology in the LifeCycle Project - EU Child Cohort Network: A Cohort Description.

Johanna L Nader, Mònica López-Vicente, Jordi Julvez, Monica Guxens, Tim Cadman, Ahmed Elhakeem, Marjo-Riitta Järvelin, Nina Rautio, Jouko Miettunen, Hanan El Marroun and 28 more

Open access · goldAbstract read
In one paragraph

Article in Journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 14 countries.

Johanna L NaderDepartment of Genetics and Bioinformatics, Division of Health Data and Digitalisation, Norwegian Institute of Public Health.ORCID 0000-0002-2045-1269
Mònica López-VicenteISGlobal, Instituto de Salud Global de Barcelona.
Jordi JulvezISGlobal, Instituto de Salud Global de Barcelona.
Monica GuxensISGlobal, Instituto de Salud Global de Barcelona.
Tim CadmanMRC Integrative Epidemiology Unit at University of Bristol, Population Health Sciences, Bristol Medical School.
Ahmed ElhakeemMRC Integrative Epidemiology Unit at University of Bristol, Population Health Sciences, Bristol Medical School.ORCID 0000-0001-7637-6360
Marjo-Riitta JärvelinCenter for Life Course Health Research, University of Oulu.
Nina RautioCenter for Life Course Health Research, University of Oulu.
Jouko MiettunenCenter for Life Course Health Research, University of Oulu.
Hanan El MarrounDepartment of Child and Adolescent Psychiatry, Erasmus University Medical Center.
Maria MelchiorInstitut national de la santé et de la recherche médicale, Institut Pierre Louis d'Épidémiologie et de Santé Publique, Sorbonne Université.
Barbara HeudeCentre for Research in Epidemiology and Statistics, Institut national de la santé et de la recherche médicale, Institut national de la recherche agronomique, Université de Paris.
Marie-Aline CharlesCentre for Research in Epidemiology and Statistics, Institut national de la santé et de la recherche médicale, Institut national de la recherche agronomique, Université de Paris.
Tiffany C YangBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust.
Rosemary R C McEachanBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust.
John WrightBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust.
Kinga PolanskaDepartment of Hygiene and Epidemiology, Medical University of Lodz.
Jennie CarsonTelethon Kids Institute, University of Western Australia.ORCID 0000-0001-5294-7536
Ashleigh LinTelethon Kids Institute, University of Western Australia.
Sebastian RauschertTelethon Kids Institute, University of Western Australia.
Rae-Chi HuangTelethon Kids Institute, University of Western Australia.
Maja PopovicCancer Epidemiology Unit, Department of Medical Sciences, University of Turin and CPO Piemonte.
Lorenzo RichiardiCancer Epidemiology Unit, Department of Medical Sciences, University of Turin and CPO Piemonte.
Eva CorpeleijnDepartment of Epidemiology, University Medical Center Groningen.
Marloes CardolDepartment of Epidemiology, University Medical Center Groningen.
Tuija M MikkolaFolkhälsan Research Center.
Johan G ErikssonFolkhälsan Research Center.
Theodosia SalikaMedical Research Council Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton.
Hazel InskipMedical Research Council Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton.
Johan Lerbech VintherSection of Epidemiology, Department of Public Health, University of Copenhagen.
Katrine Strandberg-LarsenSection of Epidemiology, Department of Public Health, University of Copenhagen.
Kathrin GürlichDivision of Metabolic and Nutritional Medicine, Department of Pediatrics, Dr von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University of Munich.
Veit GroteDivision of Metabolic and Nutritional Medicine, Department of Pediatrics, Dr von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University of Munich.
Berthold KoletzkoDivision of Metabolic and Nutritional Medicine, Department of Pediatrics, Dr von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University of Munich.
Marina VafeiadiDepartment of Social Medicine, Faculty of Medicine, University of Crete.
Jordi SunyerISGlobal, Instituto de Salud Global de Barcelona.
Vincent W V JaddoeDepartment of Pediatrics, Erasmus University Medical Center.
Jennifer R HarrisDivision of Health Data and Digitalization, Center for Fertility and Health and Department of Genetics and Bioinformatics, The Norwegian Institute of Public Health.
Erasmus MC · NLThe Kids Research Institute Australia · AUBradford Teaching Hospitals NHS Foundation Trust · GBLudwig-Maximilians-Universität München · DENorwegian Institute of Public Health · NOPiedmont Reference Center for Epidemiology and Cancer Prevention · ITSouthampton General Hospital · GBUniversity Medical Center Groningen · NLUniversity of Bristol · GBUniversity of Copenhagen · DKUniversity of Oulu · FIAgency for Science, Technology and Research · SGBarcelona Institute for Global Health · ESInstitut de Recerca Biomèdica Catalunya Sud · ESInstitut national d'études démographiques · FRMedical University of Lodz · PLOulu University Hospital · FISorbonne Université · FRUniversity of Crete · GRUniversity of Helsinki · FI

Funding

Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MC_UU_12011/4
6 · The paper itself

Abstract

backgroundThe EU LifeCycle Project was launched in 2017 to combine, harmonize, and analyze data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview of the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project.

methodsData on cognitive, behavioral, and psychological development has been collected on participants from birth until adulthood through questionnaire and medical data. We developed an inventory of the available data by mapping individual instruments, domain types, and age groups, providing the basis for statistical harmonization across mental health measures.

resultsThe mental health data in LifeCycle contain longitudinal and cross-sectional data from birth throughout the life course, covering domains across a wide range of behavioral and psychopathology indicators and outcomes, including executive function, depression, ADHD, and cognition. These data span a unique combination of qualitative data collected through behavioral/cognitive/mental health questionnaires and examination, as well as data from biological samples and indices in the form of imaging (MRI, fetal ultrasound) and DNA methylation data. Harmonized variables on a subset of mental health domains have been developed, providing statistical equivalence of measures required for longitudinal meta-analyses across instruments and cohorts.

conclusionMental health data harmonized through the LifeCycle project can be used to study life-course trajectories and exposure-outcome models that examine early life risk factors for mental illness and develop predictive markers for later-life disease.

Indexed as

Mental DisordersAdultAustraliaChildCross-Sectional StudiesHumansJapanMental Healthbirth and pregnancy cohortschild behavior and mental healthchild developmentDataSHIELDpopulation epidemiology

Identifiers

PMID34776498
PMCPMC10165218
OpenAlexW3212375285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.