Evidence map›Paper›PMID 34776428›Full record

ArticleNeuroRehabilitation2021

Patterns of balance loss with systematic perturbations in Parkinson's disease and multiple sclerosis.

Diane D Allen, Jessica Gadayan, Rebecca Hughes, Christine Magdalin, Catherine Jang, Amy Schultz, Kathryn Scott, Leah Vivero, Rolando L Lazaro, Gail L Widener

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroRehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Diane D AllenGraduate Program in Physical Therapy, University of California San Francisco/San Francisco State University, San Francisco, CA, USA.
Jessica GadayanAlbany Physical Therapy, Albany, CA, USA.
Rebecca HughesBaylor University Medical Center, Dallas, TX, USA.
Christine MagdalinKaiser San Francisco, San Francisco, CA, USA.
Catherine JangDuke Health, Hanover, MD, USA.
Amy SchultzRed Bull Athlete Performance Center, Red Bull Media House, Santa Monica, MA, USA.
Kathryn ScottVeterans Affairs Rocky Mountain Regional Health Care System, Aurora, CO, USA.
Leah ViveroDepartment of Veterans Affairs, Milpitas, CA, USA.
Rolando L LazaroSacramento State University, Sacramento, CA, USA.
Gail L WidenerPhysical Therapy, Samuel Merritt University, Oakland, CA, USA.
Baylor University Medical Center · USCalifornia State University, Sacramento · USDuke University Health System · USKaiser Permanente San Francisco Medical Center · USRegional Health · USSamuel Merritt University · USUniversity of California, San Francisco · US

Funding

Movement Ability Changes with Balance-Based Torso-Weighting in Multiple SclerosisR15HD066397 · NICHD · SAMUEL MERRITT UNIVERSITY · PI ALLEN, DIANE DAMERON, WIDENER, GAIL L. · 2010 to 2010
$413k
NICHD NIH HHS R15 HD066397
6 · The paper itself

Abstract

backgroundMultiple sclerosis (MS) and Parkinson's disease (PD) may affect balance differently. However, no studies have compared loss of balance (LOB) patterns following multi-directional perturbations.

objective1) determine reliability of LOB ratings following standardized manual perturbations; 2) compare LOB ratings in MS, PD, and healthy control (HC) groups following perturbations at upper/lower torso, in anterior/posterior, right/left, and rotational directions.

methods1) reviewers rated videotaped LOB following perturbations applied by 4 clinicians in 6-10 HCs. 2) three groups (64 MS, 42 PD and 32 HC) received perturbations. LOB ratings following perturbations were analyzed using two-factor mixed ANOVAs for magnitude and prevalence.

results1) LOB ratings showed moderate to good ICC and good to excellent agreement. 2) MS group showed greater magnitude and prevalence of LOB than PD or HC groups (p < .001). All groups showed greater LOB from right/left versus anterior/posterior perturbations (p < .01). PD showed greater LOB from perturbations at upper versus lower torso; MS and HC showed greater LOB from posterior versus anterior perturbations.

conclusionsOur reliable rating scale showed differences in patterns of LOB following manual perturbations in MS, PD, and HC. Clinically accessible and reliable assessment of LOB could facilitate targeted perturbation-based interventions and reduce falls in vulnerable populations.

Indexed as

Multiple SclerosisParkinson DiseaseHumansPostural BalanceReproducibility of ResultsTorsoassessmentbalancemultiple sclerosisParkinson’s diseaseperturbationsreliability

Identifiers

PMID34776428
PMCPMC8764603
OpenAlexW3213395941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.