Evidence map›Paper›PMID 34776007›Full record

ArticleTropical medicine and health2021

Clinical manifestations, complications, and outcomes of patients with COVID-19 in Sudan: a multicenter observational study.

Elfatih A Hasabo, Fatima A Ayyad, Sara A M Alam Eldeen, Malaz K Noureldaim, Tibyan A Abdallah, Yousra T Ahmed, Safaa Badi, Waleed K Khalid, Hind A Mirghani, Yossra A Mohammed and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 1 country.

Elfatih A HasaboFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan. elfatih.ahmed.hasabo@gmail.com.ORCID http://orcid.org/0000-0001-9727-8620
Fatima A AyyadSchool of Medicine, Ahfad University for Women, Khartoum, Sudan.
Sara A M Alam EldeenFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Malaz K NoureldaimFaculty of Medicine, National Ribat University, Khartoum, Sudan.
Tibyan A AbdallahFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Yousra T AhmedFaculty of Medical Laboratory, University of Alzaiem Alazhari, Khartoum, Sudan.
Safaa BadiFaculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan.
Waleed K KhalidSudan Medical Specialization Board, Khartoum, Sudan.
Hind A MirghaniSchool of Medicine, Ahfad University for Women, Khartoum, Sudan.
Yossra A MohammedFederal Ministry of Health, Khartoum, Sudan.
Lubaba A AlkhiderFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Saada A HamadFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Amna M TagelseedFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Ethar H A ElsheikhFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Noon H KhalidFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Samia A MohammedFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Sara O ElmobarkFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Ola O AliFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Duaa A Mohammed AliFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Mohamed S MuneerFaculty of Medicine, University of Khartoum, ElQasr Avenue, Khartoum, Khartoum state, 11111, Sudan.
Heitham AwadallaDepartment of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Elfatih M MalikDepartment of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
University of Khartoum · SDAhfad University for Women · SDAlzaiem Alazhari University · SDFederal Ministry of Health · SDNational Ribat University · SDOmdurman Islamic University · SDSudan Medical Specialization Board · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) is a pandemic caused by a newly discovered coronavirus. Although clinical manifestations of COVID-19 are mainly pulmonary, some patients have other systemic manifestations. This study aimed to describe the clinical finding and outcomes in Sudanese patients diagnosed with COVID-19.

methodsThis retrospective observational study is based on documented files that included patients diagnosed with COVID-19 in seven selected hospitals inside Khartoum. Clinical manifestations, complications and outcomes were extracted from patients' records using an extraction form designed for this study.

resultsData of 243 patients diagnosed with COVID-19 were analyzed. The mean (SD) age in years was 55.8 (18.4). Out of 116 participants, 27 of them (23.3%) had severe disease, 15 (12.9%) were critically ill. 67.5% of patients were admitted to the hospital within 7 days from onset of symptoms; most of them were admitted to the wards (n = 140,72.5%). Fever (83.2%), cough (70.7%), and shortness of breath (69.2%) were the most commonly recorded clinical manifestations. Sepsis (9.8%) and acidosis (7.8%) were the most frequently reported complications. Death was the final outcome in 21.4% (56/243). Older age and presence of diabetes were found significantly associated with in-hospital death. The laboratory results showed high CRP in 85.6% (119/139), high ferritin in 88.9% (24/27), lactate dehydrogenase had a median of 409.0 (359-760), D-dimer had a median of 3.3 (1.2-16. 6), and 53/105 (50.5%) had low albumin.

conclusionsFever was the most mentioned sign among the participants, followed by fatigue. Cough and shortness of breath were the most commonly recorded pulmonary symptoms manifested. Our study showed multiple variables were associated with in-hospital death. The mortality rate was high among severe and critically ill patients diagnosed with COVID-19.

Indexed as

Clinical manifestationsComplicationsCOVID-19In-hospital outcomesSeveritySudan

Identifiers

PMID34776007
PMCPMC8590864
OpenAlexW3214279925

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.