Evidence map›Paper›PMID 34775789›Full record

ArticleHypertension (Dallas, Tex. : 1979)2022

Twenty-Four-Hour Central (Aortic) Systolic Blood Pressure: Reference Values and Dipping Patterns in Untreated Individuals.

Thomas Weber, Athanase D Protogerou, Mohsen Agharazii, Antonis Argyris, Sola Aoun Bahous, Jose R Banegas, Ronald K Binder, Jacques Blacher, Andréa Araujo Brandao, Juan J Cruz and 27 more

Open access · hybridAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. 24-hour isolated aortic systolic hypertension phenotype and its association with carotid and cardiac damage: the SAFAR study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Another step forward in the introduction of aortic systolic blood pressure assessment into clinical practice?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  13. 24-h central pressure is a valuable predictor for left ventricular hypertrophy in non-dialysis patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Central hypertension is a non-negligible cardiovascular risk factor.Journal of clinical hypertension (Greenwich, Conn.) · 2022
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 20 institutions in 15 countries.

Thomas WeberCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).ORCID 0000-0003-0617-0417
Athanase D ProtogerouCardiovascular Prevention and Research Unit, Clinic-Laboratory of Pathophysiology and First Department of Propeadeutic Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece (A.D.P., A.A., P.P.S.).
Mohsen AgharaziiCentre de Recherche Du CHU de Québec, Université Laval, Canada (M.A.).
Antonis ArgyrisCardiovascular Prevention and Research Unit, Clinic-Laboratory of Pathophysiology and First Department of Propeadeutic Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece (A.D.P., A.A., P.P.S.).ORCID 0000-0002-8906-6959
Sola Aoun BahousLebanese American University School of Medicine, Byblos, Lebanon (S.A.B.).
Jose R BanegasDepartment of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ and CIBER in Epidemiology and Public Health, Spain (J.R.B., J.J.C., A.G.).ORCID 0000-0001-6152-9862
Ronald K BinderCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).
Jacques BlacherAP-HP Centre-Université de Paris, Hôpital Hôtel-Dieu, Centre de diagnostic et de thérapeutique, France (J.B., A.V.).
Andréa Araujo BrandaoState University of Rio de Janeiro, Brazil (A.A.B.).
Juan J CruzDepartment of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ and CIBER in Epidemiology and Public Health, Spain (J.R.B., J.J.C., A.G.).
Kathrin DanningerCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).
Cristina GiannatasioSchool of Medicine and Surgery, Milano-Bicocca University and Cardiology 4, ASST GOM Niguarda, Milan, Italy (C.G., A.M.).
Auxiliadora GracianiDepartment of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ and CIBER in Epidemiology and Public Health, Spain (J.R.B., J.J.C., A.G.).
Bernhard HametnerAustrian Institute of Technology, Vienna, Austria (B.H., C.C.M., S.W.).ORCID 0000-0003-2048-1019
Piotr JankowskiInstitute of Cardiology, Jagellonian University, Krakow, Poland (P.J.).ORCID 0000-0001-6223-8821
Yan LiCentre for Vascular Evaluations, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (Y.L.).
Alessandro MalobertiSchool of Medicine and Surgery, Milano-Bicocca University and Cardiology 4, ASST GOM Niguarda, Milan, Italy (C.G., A.M.).ORCID 0000-0002-2612-6264
Christopher C MayerAustrian Institute of Technology, Vienna, Austria (B.H., C.C.M., S.W.).
Barry J McDonnellCardiff School of Sport and Health Sciences, Cardiff Metropolitan University, United Kingdom (B.J.M.).ORCID 0000-0001-5912-1278
Carmel M McEnieryCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).
Marco Antonio Mota GomesCentro Universitario CESMAC, Alagoas, Brazil (M.A.M.G., A.M.G.).ORCID 0000-0002-6652-1533
Annelise Machado GomesCentro Universitario CESMAC, Alagoas, Brazil (M.A.M.G., A.M.G.).ORCID 0000-0001-9475-3166
Maria Lorenza MuiesanDepartment of Clinical and Experimental Sciences, Centro per la Prevenzione e Cura dell'ipertensione Arteriosa, University of Brescia and ASST Spedali Civili, Italy (M.L.M., A.P.).ORCID 0000-0002-4007-9441
Janos NemcsikDepartment of Family Medicine, Semmelweis University, Budapest, Hungary (J.N.).
Anna PainiDepartment of Clinical and Experimental Sciences, Centro per la Prevenzione e Cura dell'ipertensione Arteriosa, University of Brescia and ASST Spedali Civili, Italy (M.L.M., A.P.).
Enrique RodillaUniversidad Cardenal Herrera-CEU, CEU Universities, Hospital de Sagunto, Valencia, Spain (E.R.).
Aletta E SchutteSchool of Population Health, University of New South Wales, Sydney, Australia (A.E.S.).
Petros P SfikakisCardiovascular Prevention and Research Unit, Clinic-Laboratory of Pathophysiology and First Department of Propeadeutic Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece (A.D.P., A.A., P.P.S.).
Dimitrios Terentes-PrintziosFirst Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece (D.T.-P., C.V.).ORCID 0000-0003-4039-8263
Alexandre ValléeAP-HP Centre-Université de Paris, Hôpital Hôtel-Dieu, Centre de diagnostic et de thérapeutique, France (J.B., A.V.).
Charalambos VlachopoulosCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).ORCID 0000-0002-9904-3558
Lisa WareDSI-NRF Centre of Excellence in Human Development, University of the Witwatersrand, South Africa (L.W.).
Ian WilkinsonExperimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, United Kingdom (C.M.M., I.W.).
Robert ZweikerCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).
James E SharmanCardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).ORCID 0000-0003-2792-0811
Siegfried WassertheurerAustrian Institute of Technology, Vienna, Austria (B.H., C.C.M., S.W.).
International Academic 24-Hour Ambulatory Aortic Blood Pressure Consortium (i24abc.org)Cardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).
Klinikum Wels-Grieskirchen · ATAustrian Institute of Technology · ATCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESNational and Kapodistrian University of Athens · GRAssistance Publique – Hôpitaux de Paris · FRAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCentro Universitário Cesmac · BRAddenbrooke's Hospital · GBCardiff Metropolitan University · GBCentre hospitalier de l'Université Laval · CAHippocration General Hospital · GRKrakow Cardiovascular Research Institute · PLLebanese American University · LBPathways Behavioral Services · USSemmelweis University · HUShanghai Institute of Hypertension · CNThe University of Sydney · AUUniversidad Cardenal Herrera CEU · ESUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central (aortic) systolic blood pressure (cSBP) is the pressure seen by the heart, the brain, and the kidneys. If properly measured, cSBP is closer associated with hypertension-mediated organ damage and prognosis, as compared with brachial SBP (bSBP). We investigated 24-hour profiles of bSBP and cSBP, measured simultaneously using Mobilograph devices, in 2423 untreated adults (1275 women; age, 18-94 years), free from overt cardiovascular disease, aiming to develop reference values and to analyze daytime-nighttime variability. Central SBP was assessed, using brachial waveforms, calibrated with mean arterial pressure (MAP)/diastolic BP (cSBP

Indexed as

AdolescentAdultAgedAged, 80 and overArterial PressureBlood PressureBlood Pressure DeterminationBrachial ArteryCircadian RhythmFemaleHumansMaleMiddle AgedReference ValuesYoung Adultarterial pressureblood pressureheart ratehypertension

Identifiers

PMID34775789
PMCPMC8654125
OpenAlexW3213783643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.