Evidence map›Paper›PMID 34775667›Full record

ArticleEuropean journal of neurology2022

Protective factors for subjective cognitive decline individuals: trajectories and changes in a longitudinal study with Italian elderly.

Sara Mondini, Veronica Pucci, Sonia Montemurro, Raffaella Ida Rumiati

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  13. Cognitive reserve modulates mental health in adulthood.Aging clinical and experimental research · 2024
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  18. Tele-Global Examination of Mental State (Tele-GEMS): an open tool for the remote neuropsychological screening.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Sara MondiniDepartment of Philosophy, Sociology, Education and Applied Psychology, FISPPA, University of Padua, Padua, Italy.ORCID 0000-0002-2144-9435
Veronica PucciDepartment of Philosophy, Sociology, Education and Applied Psychology, FISPPA, University of Padua, Padua, Italy.
Sonia MontemurroIRCCS San Camillo Hospital, Venice, Italy.
Raffaella Ida RumiatiNeuroscience, SISSA, Triest, Italy.
University of Padua · ITIRCCS San Camillo Hospital · ITScuola Internazionale Superiore di Studi Avanzati · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMany different factors have been hypothesized to modulate cognition in an aging population according to their functioning at baseline.

methodsThis retrospective study quantifies the relative contribution of age and sex as demographic factors, comorbidity, education and occupation (classified with the International Standard Classification of Occupation 2008) as cognitive reserve proxies in accounting for cognitive aging. All participants (3081) were evaluated at baseline with a complete neuropsychological test battery (T1) and those with unimpaired profiles were classified as subjective cognitive decline, those mildly impaired as mild neurocognitive decline and those severely impaired as major neurocognitive decline. From the first assessment 543 individuals were assessed a second time (T2), and 125 a third time (T3). Depending on whether they maintained or worsened their profile, based on their initial performance, participants were then classified as resistant or declining.

resultsAt baseline, all individuals showed education and occupation as the best predictors of performance, in addition to age. Furthermore, across assessments, the resistant had higher levels of education and occupation than the declining. In particular, the education and occupation predicted cognitive performance in all groups considered, from the subjective cognitive decline to the one with the most severely impaired participants.

conclusionsThis study highlights the role of working activity in protecting from cognitive decline across all fragile elderly groups and even more so the individuals who are at very high risk of decline.

Indexed as

Cognitive DysfunctionCognitive ReserveAgedCognitionHumansLongitudinal StudiesNeuropsychological TestsProtective FactorsRetrospective Studiescognitive declinecognitive reservedementiaeducationoccupation

Identifiers

PMID34775667
PMCPMC9299717
OpenAlexW3211847123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.