Evidence map›Paper›PMID 34775619›Full record

ArticleMagnetic resonance in medicine2022

Optimization of pseudo-continuous arterial spin labeling using off-resonance compensation strategies at 7T.

Gaël Saïb, Alan P Koretsky, S Lalith Talagala

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Dynamic BMagnetic resonance in medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gaël SaïbNINDS/LFMI, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0003-2571-2410
Alan P KoretskyNINDS/LFMI, National Institutes of Health, Bethesda, Maryland, USA.
S Lalith TalagalaNINDS/NMRF, National Institutes of Health, Bethesda, Maryland, USA.
National Institutes of Health · US

Funding

Functional Imaging of The BrainZIANS002989 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KORETSKY, ALAN · 2009 to 2025
$41.5M
MRI Engineering TeamZICNS009425 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KORETSKY, ALAN · 2021 to 2025
$11.6M
Intramural NIH HHS ZIA NS002989
6 · The paper itself

Abstract

purposeThe sensitivity of pseudo-continuous arterial spin labeling (PCASL) to off-resonance effects (ΔB THEORY AND

methodsPhase offset errors induced by ΔB

resultsThe perfusion signal was more uniform throughout the brain after off-resonance correction. Whole-brain average perfusion signal increased by a factor of 2.4, 2.5, and 2.1, respectively, with AVGcor, FMcor and PScor compared to acquisitions without correction. With off-resonance correction, the maximum labeling efficiency was ~0.68 at mean B

conclusionEither a prescan or a field map can be used to correct for off-resonance effects and retrieve a good brain perfusion signal at 7T. Although the three methods performed well in this study, FMcor may be better suited for patient studies because it accounted for vessel-specific ΔB

Indexed as

ArteriesCerebrovascular CirculationBrainHumansMagnetic Resonance AngiographyPerfusionSpin LabelsSpin LabelsASLlabeling efficiencyMRIoff-resonance effectspseudo-continuous arterial spin labeling (PCASL)ultra-high field (UHF)

Identifiers

PMID34775619
PMCPMC8810716
OpenAlexW3211736610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.