ArticleGait & posture2022
Knee biomechanics and contralateral knee osteoarthritis progression after total knee arthroplasty.
Article in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Step-by-step insight into gait analysis: A narrative review unlocking knee biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Review
- Article
- Kinematic and Kinetic Variables Associated With the Contralateral Knee Adduction Moment During Walking After Medial Open-Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Kinematic alignment yields a reduced knee adduction moment and better range of motion compared to mechanical alignment: biomechanical considerations of a staged, bilateral total knee arthroplasty case.BMC musculoskeletal disorders · 2026Article
- Clinical value of biomechanics and magnetic resonance imaging in the evaluation of knee osteoarthritis.Frontiers in surgery · 2026Article
- Postoperative Functional Mobility and Quality of Life in Patients with Anteromedial Osteoarthritis of the Knee Treated with MB-UKA versus TKA.Journal of pain research · 2026Article
- Neuropathic pain in knee osteoarthritis: functional burden beyond cartilage thickness-a cross-sectional study.BMC research notes · 2025Article
- Stage-dependent effects of moderate treadmill exercise on cartilage preservation and subchondral bone remodeling in mouse osteoarthritis progression.Osteoarthritis and cartilage · 2025Article
- Preoperative and Post-Rehabilitation Predictors of Gait Biomechanics Six Months After Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Peak, cumulative and rate of medial and lateral compartment joint loading during gait following total knee arthroplasty.Gait & posture · 2025Article
- Prevalence of osteoarthritis and clinical outcomes in patients with fractures of the tibial plateau - medium- and long-term analysis.BMC musculoskeletal disorders · 2025Observational
- The Effects of Biomechanical Loading on the Tibial Insert After Primary Total Knee Arthroplasty: A Systematic Review.Journal of clinical medicine · 2025Review
- Joint modeling and marker set selection significantly influence functional biomechanics in end-stage knee osteoarthritis: evidence from the sit-to-stand task.Frontiers in bioengineering and biotechnology · 2025Article
- Intra-articular injections with Carboxymethyl-Chitosan in patients affected by knee osteoarthritis non-responders to hyaluronic acid: a pilot study.European journal of translational myology · 2024Article
- Finding the Goldilocks Zone of Mechanical Loading: A Comprehensive Review of Mechanical Loading in the Prevention and Treatment of Knee Osteoarthritis.Bioengineering (Basel, Switzerland) · 2024Review
- Morphology and transverse alignment of the patella have no effect on knee gait characteristics in healthy Chinese adults over the age of 40 years.Frontiers in bioengineering and biotechnology · 2024Article
- The Immediate Effect of Backward Walking on External Knee Adduction Moment in Healthy Individuals.Journal of healthcare engineering · 2022Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundDespite the success rate of Total Knee Arthroplasty (TKA), many patients undergo contralateral TKA. It is possible that altered gait mechanics after unilateral TKA play a role in the progression of contralateral OA progression. RESEARCH QUESTION: The purpose of this study was to identify biomechanical predictors of radiographic OA progression in the contralateral (non-surgical) knee after unilateral (primary/initial) TKA. In addition, this study quantified for patients who had contralateral OA progression.
methodsBiomechanical outcomes were collected 6-24 months after unilateral primary TKA and were used to predict changes in contralateral OA severity at follow-up. Participants were divided into "Progressor" and "Non-Progressor" groups based on changes in Kellgren-Lawrence (KL) OA grade and Joint Space Width (JSW) between baseline and follow-up testing sessions. Biomechanical factors during walking were peak knee adduction moment, knee flexion/extension excursions, knee angle at initial foot contact, and peak knee flexion/extension. Multiple independent t-tests were used to examine the magnitude of differences in biomechanical variables between the groups. Logistic regression was used to examine the association between the biomechanical predictors and change in KL scores and JSW.
resultsThe mean time between surgery and follow-up x-rays was 8.8 (2.4) years. Of 40 participants, 62.5-78% had contralateral radiographic knee OA progression by follow-up. There were no significant differences in the biomechanical variables between groups. For the regression analysis, none of the biomechanical variables were found to be predictors for contralateral OA progression. SIGNIFICANCE: Although abnormal biomechanics are known risk factors for primary knee OA, it is possible that the mechanisms that result in OA progression of the contralateral limb are different than primary knee OA progression. Future work should evaluate other objective measures of OA progression and determine if cumulative measures of joint loading are related to OA worsening.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.