Evidence map›Paper›PMID 34775144›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2021

A metagenomics workflow for SARS-CoV-2 identification, co-pathogen detection, and overall diversity.

Daniel Castañeda-Mogollón, Claire Kamaliddin, Lisa Oberding, Yan Liu, Abu Naser Mohon, Rehan Mujeeb Faridi, Faisal Khan, Dylan R Pillai

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Analysis of metagenomic data.Nature reviews. Methods primers · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniel Castañeda-MogollónCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada.
Claire KamaliddinCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada.
Lisa OberdingCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada.
Yan LiuCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada.
Abu Naser MohonCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada.
Rehan Mujeeb FaridiAlberta Precision Laboratories, Diagnostic & Scientific Centre, Calgary, AB, Canada; Hematology Translational Lab, University of Calgary, Calgary, AB, Canada; Arnie Charbonneau Cancer Institute, the University of Calgary, Calgary, AB, Canada.
Faisal KhanAlberta Precision Laboratories, Diagnostic & Scientific Centre, Calgary, AB, Canada; Hematology Translational Lab, University of Calgary, Calgary, AB, Canada; Arnie Charbonneau Cancer Institute, the University of Calgary, Calgary, AB, Canada.
Dylan R PillaiCumming School of Medicine, Department of Pathology & Laboratory Medicine, the University of Calgary, AB, Canada; Cumming School of Medicine, Department of Microbiology, Immunology, and Infectious Diseases, the University of Calgary, Canada; Calvin, Phoebe & Joan Snyder Institute for Chronic Diseases, the University of Calgary, Calgary, AB, Canada; Alberta Precision Laboratories, Diagnostic & Scientific Centre, Calgary, AB, Canada. Electronic address: drpillai@ucalgary.ca.
University of Calgary · CACalgary Laboratory Services · CAInstitute of Cancer Research · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An unbiased metagenomics approach to virus identification can be essential in the initial phase of a pandemic. Better molecular surveillance strategies are needed for the detection of SARS-CoV-2 variants of concern and potential co-pathogens triggering respiratory symptoms. Here, a metagenomics workflow was developed to identify the metagenome diversity by SARS-CoV-2 diagnosis (n

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingHumansMetagenomicsWorkflowCOVID-19MetagenomicsSARS-CoV-2Variants of ConcernVariants of Interest

Identifiers

PMID34775144
PMCPMC8564975
OpenAlexW3208208548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.