Evidence map›Paper›PMID 34774824›Full record

ArticleAmerican journal of obstetrics and gynecology2022

Preterm birth after the introduction of COVID-19 mitigation measures in Norway, Sweden, and Denmark: a registry-based difference-in-differences study.

Laura L Oakley, Anne K Örtqvist, Jonas Kinge, Anne Vinkel Hansen, Tanja Gram Petersen, Jonas Söderling, Kjetil E Telle, Maria C Magnus, Laust Hvas Mortensen, Anne-Marie Nybo Andersen and 2 more

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura L OakleyDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway. Electronic address: laura.oakley@lshtm.ac.uk.
Anne K ÖrtqvistClinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Department of Obstetrics and Gynaecology, Visby County Hospital, Visby, Sweden.
Jonas KingeCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway; University of Oslo, Oslo, Norway.
Anne Vinkel HansenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark; Statistics Denmark, Copenhagen, Denmark.
Tanja Gram PetersenOpen Patient Data Explorative Network, Odense University Hospital, Odense, Denmark.
Jonas SöderlingClinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Kjetil E TelleDivision for Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Maria C MagnusCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway; Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.
Laust Hvas MortensenStatistics Denmark, Copenhagen, Denmark; Population Health Sciences, Bristol Medical School, Bristol, United Kingdom.
Anne-Marie Nybo AndersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Olof StephanssonClinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Department of Women's Health, Karolinska University Hospital, Solna, Stockholm, Sweden.
Siri E HåbergCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough some studies have reported a decrease in preterm birth following the start of the COVID-19 pandemic, the findings are inconsistent.

objectiveThis study aimed to compare the incidences of preterm birth before and after the introduction of COVID-19 mitigation measures in Scandinavian countries using robust population-based registry data. STUDY

designThis was a registry-based difference-in-differences study using births from January 2014 through December 2020 in Norway, Sweden, and Denmark. The changes in the preterm birth (<37 weeks) rates before and after the introduction of COVID-19 mitigation measures (set to March 12, 2020) were compared with the changes in preterm birth before and after March 12 from 2014 to 2019. The differences per 1000 births were calculated for 2-, 4-, 8-, 12-, and 16-week intervals before and after March 12. The secondary analyses included medically indicated preterm birth, spontaneous preterm birth, and very preterm (<32 weeks) birth.

resultsA total of 1,519,521 births were included in this study. During the study period, 5.6% of the births were preterm in Norway and Sweden, and 5.7% were preterm in Denmark. There was a seasonal variation in the incidence of preterm birth, with the highest incidence during winter. In all the 3 countries, there was a slight overall decline in preterm births from 2014 to 2020. There was no consistent evidence of a change in the preterm birth rates following the introduction of COVID-19 mitigation measures, with difference-in-differences estimates ranging from 3.7 per 1000 births (95% confidence interval, -3.8 to 11.1) for the first 2 weeks after March 12, 2020, to -1.8 per 1000 births (95% confidence interval, -4.6 to 1.1) in the 16 weeks after March 12, 2020. Similarly, there was no evidence of an impact on medically indicated preterm birth, spontaneous preterm birth, or very preterm birth.

conclusionUsing high-quality national data on births in 3 Scandinavian countries, each of which implemented different approaches to address the pandemic, there was no evidence of a decline in preterm births following the introduction of COVID-19 mitigation measures.

Indexed as

COVID-19Premature BirthDenmarkHumansInfant, NewbornPandemicsRegistriesSwedenCOVID-19pregnancy outcomespreterm birthretrospectiveScandinavia

Identifiers

PMID34774824
PMCPMC8648397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.