Evidence map›Paper›PMID 34774585›Full record

ReviewPharmacology, biochemistry, and behavior2021

Behavioral and pharmacological interventions for the prevention and treatment of psychiatric disorders with children exposed to maltreatment.

Chad E Shenk, Brooks Keeshin, Heather E Bensman, Anneke E Olson, Brian Allen

Abstract readReview
In one paragraph

Review in Pharmacology, biochemistry, and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Transdiagnostic prevention in youth mental health, Part II: interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Article
  3. A Longitudinal Analysis of Concerning Psychotropic Medication Regimens Among Adolescents in Foster Care.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chad E ShenkDepartment of Human Development and Family Studies, The Pennsylvania State University, 115 Health and Human Development Building, University Park, PA 16802, USA; Department of Pediatrics, The Pennsylvania State University College of Medicine, 700 HMC Crescent Road, Hershey, PA 17033, USA. Electronic address: ces140@psu.edu.
Brooks KeeshinDepartment of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA; Department of Psychiatry, University of Utah, 5021 Chipeta Way, Salt Lake City, UT 84108, USA. Electronic address: brooks.keeshin@hsc.utah.edu.
Heather E BensmanCincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Electronic address: heather.bensman@cchmc.org.
Anneke E OlsonDepartment of Human Development and Family Studies, The Pennsylvania State University, 115 Health and Human Development Building, University Park, PA 16802, USA. Electronic address: aeo442@psu.edu.
Brian AllenDepartment of Pediatrics, The Pennsylvania State University College of Medicine, 700 HMC Crescent Road, Hershey, PA 17033, USA; Department of Psychiatry and Behavioral Health, The Pennsylvania State University College of Medicine, 700 HMC Crescent Road, Hershey, PA 17033, USA. Electronic address: ballen1@pennstatehealth.psu.edu.

Funding

STRATIFIED CLUSTER RANDOMIZED TRIAL (SCRT) OF A CLINICAL DECISION RULE (CDR) FOR ABUSIVE HEAD TRAUMA (AHT)P50HD089922 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI CHRISTIAN M CONNELL · 2017 to 2026
$16.9M
Creating the Next Generation of Scholars in CM Science (CMT32)T32HD101390 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Erika Lunkenheimer, Hannah Milena Caroline Schreier · 2020 to 2026
$1.9M
NICHD NIH HHS P50 HD089922NICHD NIH HHS T32 HD101390
6 · The paper itself

Abstract

There is a well-established relation between exposure to child maltreatment and the onset and course of multiple, comorbid psychiatric disorders. Given the heterogeneous clinical presentations at the time services are initiated, interventions for children exposed to maltreatment need to be highly effective to curtail the lifelong burden and public health costs attributable to psychiatric disorders. The current review describes the most effective, well-researched, and widely-used behavioral and pharmacological interventions for preventing and treating a range of psychiatric disorders common in children exposed to maltreatment. Detailed descriptions of each intervention, including their target population, indicated age range, hypothesized mechanisms of action, and effectiveness demonstrated through randomized controlled trials research, are presented. Current limitations of these interventions are noted to guide specific directions for future research aiming to optimize both treatment effectiveness and efficiency with children and families exposed to maltreatment. Strategic and programmatic future research can continue the substantial progress that has been made in the prevention and treatment of psychiatric disorders for children exposed to maltreatment.

Indexed as

Child AbuseAdolescentAdverse Childhood ExperiencesBehavior TherapyChildChild, PreschoolCognitive Behavioral TherapyFemaleHumansMaleMental DisordersRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsStress Disorders, Post-TraumaticSelective Serotonin Reuptake InhibitorsBehavioral interventionsChild maltreatmentPharmacological interventionsPsychiatric disordersTransdiagnostic

Identifiers

PMID34774585
PMCPMC8643336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.