Evidence map›Paper›PMID 34774489›Full record

ArticleExperimental eye research2021

Assessment of retinal oxygen metabolism, visual function, thickness and degeneration markers after variable ischemia/reperfusion in rats.

Nathanael Matei, Sophie Leahy, Norman P Blair, Mahnaz Shahidi

Open access · greenAbstract read
In one paragraph

Article in Experimental eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Retinal Hypoxia: Relation to Blood Flow and Oxygen Metabolic Biomarkers.Investigative ophthalmology & visual science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nathanael MateiDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, United States.
Sophie LeahyDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, United States.
Norman P BlairDepartment of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, United States.
Mahnaz ShahidiDepartment of Ophthalmology, University of Southern California, Los Angeles, CA, United States. Electronic address: mshahidi@usc.edu.
University of Southern California · USUniversity of Illinois Chicago · US

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
Noninvasive Imaging of Chorioretinal Oxygen TensionR01EY017918 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHAHIDI, MAHNAZ · 2007 to 2022
$6.2M
NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY017918
6 · The paper itself

Abstract

After total retinal ischemia induced experimentally by ophthalmic vessel occlusion followed by reperfusion, studies have reported alterations in retinal oxygen metabolism (MO

Indexed as

AnimalsApoptosisBlood Flow VelocityElectroretinographyGlial Fibrillary Acidic ProteinGliosisIn Situ Nick-End LabelingMaleOxygenOxygen ConsumptionRatsRats, Long-EvansRegional Blood FlowReperfusion InjuryRetinaRetinal DegenerationGfap protein, ratGlial Fibrillary Acidic ProteinOxygenOphthalmic vessel occlusionRetinal ischemiaRetinal oxygen metabolism

Identifiers

PMID34774489
PMCPMC8665131
OpenAlexW3211444222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.