ArticleVaccine2021
Persuasive messaging to increase COVID-19 vaccine uptake intentions.
Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04460703 (Persuasive Messages for COVID-19 Vaccine Uptake), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Persuasive Messages for COVID-19 Vaccine Uptake: a Randomized Controlled Trial, Part 1
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Vaccine preferences and their role for vaccine confidence and uptake: a meta-ethnography.Global health action · 2026Pooled it
- Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis.BMJ open · 2025Pooled it
- Optimizing Web Links Used in Digital Vaccination Invitations to Raise Trust and Booking Intention: 3 Online Randomized Controlled Trials.Journal of medical Internet research · 2026Trial
- Assessment of COVID-19 Messaging Strategies to Increase Testing for Students With Intellectual and Developmental Disabilities.The Journal of school health · 2024Trial
- Influencing Canadian young adults to receive additional COVID-19 vaccination shots: the efficacy of brief video interventions focusing on altruism and individualism.Frontiers in public health · 2024Trial
- Personal risk or societal benefit? Investigating adults' support for COVID-19 childhood vaccination.Vaccine · 2023Trial
- Trial
- When do persuasive messages on vaccine safety steer COVID-19 vaccine acceptance and recommendations? Behavioural insights from a randomised controlled experiment in Malaysia.BMJ global health · 2022Trial
- Balancing individual risks and collective benefits: Effects of vaccine price, message framing, and value orientations on influenza vaccination in China.Human vaccines & immunotherapeutics · 2026Article
- The AuTOMATIC trial: a multicentre digitally-automated, Bayesian, adaptive, parallel, factorial randomised controlled trial of SMS reminders for childhood vaccination.The Lancet regional health. Western Pacific · 2026Article
- How topic content shapes LLM personality-tailored persuasion: semantic anchoring and topic stereotype effects.Frontiers in psychiatry · 2026Article
- Immunisation health workforce capacity building in Southeast Asia: reflections from training programme implementation in Cambodia and Lao PDR.BMJ global health · 2025Article
- COVID-19 Vaccine Uptake: Prevalence, Health Facility Enablers and Barriers among Adult Tuberculosis Patients across Nairobi County Clinics, Kenya.Journal of tuberculosis research · 2025Article
- The influence of audience's regulatory focus on the persuasive effect of different pro-vaccine messages.PloS one · 2025Article
- The evolution of vaccine hesitancy through the COVID-19 pandemic: A semi-structured interview study on booster and bivalent doses.Human vaccines & immunotherapeutics · 2024Article
- Article
- Mobile Phone Text Message Reminders to Improve Vaccination Uptake: A Systematic Review and Meta-Analysis.Vaccines · 2024Review
- The power of the family in times of pandemic: Cross-country evidence from 93 countries.SSM - population health · 2024Article
- Behavioral nudges in social media ads show limited ability to encourage COVID-19 vaccination across countries.PNAS nexus · 2024Article
- Lay beliefs of COVID-19 vaccine refusal among intercity commercial drivers in the Volta region of Ghana: recommendations for improved vaccine uptake.Tropical diseases, travel medicine and vaccines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Widespread vaccination remains the best option for controlling the spread of COVID-19 and ending the pandemic. Despite the considerable disruption the virus has caused to people's lives, many people are still hesitant to receive a vaccine. Without high rates of uptake, however, the pandemic is likely to be prolonged. Here we use two survey experiments to study how persuasive messaging affects COVID-19 vaccine uptake intentions. In the first experiment, we test a large number of treatment messages. One subgroup of messages draws on the idea that mass vaccination is a collective action problem and highlighting the prosocial benefit of vaccination or the reputational costs that one might incur if one chooses not to vaccinate. Another subgroup of messages built on contemporary concerns about the pandemic, like issues of restricting personal freedom or economic security. We find that persuasive messaging that invokes prosocial vaccination and social image concerns is effective at increasing intended uptake and also the willingness to persuade others and judgments of non-vaccinators. We replicate this result on a nationally representative sample of Americans and observe that prosocial messaging is robust across subgroups, including those who are most hesitant about vaccines generally. The experiments demonstrate how persuasive messaging can induce individuals to be more likely to vaccinate and also create spillover effects to persuade others to do so as well. The first experiment in this study was registered at clinicaltrials.gov and can be found under the ID number NCT04460703. This study was registered at Open Science Framework (OSF) at: https://osf.io/qu8nb/?view_only=82f06ecad77f4e54b02e8581a65047d7.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.