ArticleBMC sports science, medicine & rehabilitation2021
The efficacy of intermittent pneumatic compression and negative pressure therapy on muscle function, soreness and serum indices of muscle damage: a randomized controlled trial.
Article in BMC sports science, medicine & rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06079684 (Clinical Evidence Regarding The Dynamic of Baker Cyst Dimensions After Intermittent Vacuum Therapy As Rehabilitation Treatment In Patients With Knee Osteoarthritis), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Evidence Regarding The Dynamic of Baker Cyst Dimensions After Intermittent Vacuum Therapy As Rehabilitation Treatment In Patients With Knee Osteoarthritis
Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- A randomised crossover trial comparing photobiomodulation therapy with other recovery strategies in CrossFit athletes.PloS one · 2026Trial
- Effect of pneumatic and cold compression on muscle performance and recovery in combat sports athletes.Scientific reports · 2025Trial
- Intermittent pneumatic compression does not improve post-match neuromuscular, biochemical or perceptual recovery in international-level youth soccer players: a randomized placebo-controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Myofascial release and fascial-targeted mechanical interventions in musculoskeletal rehabilitation: mechanisms, modalities, and integrative physiology.Frontiers in physiology · 2026Review
- The Potential Role of Iron Homeostasis and Ferroptosis in Exercise Nutrition and Health.Nutrients · 2026Review
- Efficacy of post-exercise recovery strategies for elite soccer players: a network meta-analysis.Frontiers in physiology · 2026Article
- Isolated and Combined Effects of Cold, Heat and Hypoxia Therapies on Muscle Recovery Following Exercise-Induced Muscle Damage.Sports medicine (Auckland, N.Z.) · 2025Review
- Effects of Pneumatic Compression and Manual Massage on Recovery and Performance in Elite Brazilian Under-20 Soccer Players: A Crossover Trial.Sports (Basel, Switzerland) · 2025Article
- Cryocompression Therapy for Recovery from Eccentric Exercise-Induced Muscle Damage in Healthy Young Men.Sports (Basel, Switzerland) · 2025Article
- Acute effects of lower-limb intermittent negative pressure on microcirculatory function in Tai Chi athletes: an exploratory study.Frontiers in physiology · 2025Article
- Health Resort Treatment Improves Functioning and Physical Performance in Long COVID Patients: A Retrospective Study.Healthcare (Basel, Switzerland) · 2024Article
- Effects of lower-limb intermittent pneumatic compression on sports recovery: A systematic review and meta-analysis.Biology of sport · 2024Review
- Optimal Duration of Cold and Heat Compression for Forearm Muscle Biomechanics in Mixed Martial Arts Athletes: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Clinical Evidence Regarding the Dynamic of Baker Cyst Dimensions after Intermittent Vacuum Therapy as Rehabilitation Treatment in Patients with Knee Osteoarthritis.Journal of clinical medicine · 2023Article
- The Effect of Pressotherapy on Performance and Recovery in the Management of Delayed Onset Muscle Soreness: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study aimed to assess whether intermittent pneumatic compression (IPC) and intermittent negative pressure (INP) would attenuate the muscle damaging effects of eccentric exercise.
methodsForty-five healthy males were recruited. Immediately post, 24 and 48 h post eccentric exercise consisting of 100 drop jumps, volunteers randomly received 30-min sessions of intermittent pneumatic compression (IPC, n = 15) or intermittent negative pressure (INP, n = 15), or sham microcurrent (PT, n = 15). Creatine kinase (CK), lactate dehydrogenase (LDH), isokinetic muscle strength, soreness and active flexion of the knee joint were measured after every therapy session.
resultsNo significant intergroup differences were observed in biochemical or functional measurements. However, there was an increase in muscle soreness (P < 0.05), CK and LDH activity (P < 0.05), and a reduction in muscle strength (P < 0.05) and range of active knee flexion (P < 0.05).
conclusionsThe prescription of IPC and INP did not attenuate the reduction of markers to muscle function or pain perception up to 48 h after muscle damaging exercise. Future research should focus on the potential impact of treatment frequency and duration on muscle recovery. Trial registration The study was retrospectively registered in the Australian New Zealand Clinical Trials Registry (ANZCTR); The trial registration number: ACTRN12621001294842; date of registration: 24/09/2021.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.