ArticleNutrition & metabolism2021
Fluctuations in waist circumference increase diabetes risk: a 4-year cohort study in 61,587 older adults.
Article in Nutrition & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The association of plant or animal food origin and processing level with BMI and waist circumference: a prospective cohort study of the UK Biobank.EClinicalMedicine · 2026Article
- Changes in body mass index and waist circumference as predictors of incident prediabetes: the Aichi Workers' Cohort Study.Scientific reports · 2026Article
- Sex and age differences in the association between obesity and long-term changes with the risk of incident type 2 diabetes mellitus: the Rural Deqing Cohort Study.Hepatobiliary surgery and nutrition · 2026Article
- Glycemic load, glycemia, and self-reported diabetes mellitus in community-dwelling older adults: a 24-hour dietary recall-based assessment.Journal of diabetes and metabolic disorders · 2025Article
- A Holistic Approach to Metabolic Health Assessment-Analysis of Bioimpedance, Blood, and Saliva Biochemistry in Population Studies-A Pilot Study.Metabolites · 2025Article
- Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program.Diabetes & metabolism journal · 2023Article
- Obesity- and lipid-related indices as a predictor of type 2 diabetes in a national cohort study.Frontiers in endocrinology · 2023Article
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Authors and funding
9 authors.
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Abstract
purposeTo evaluate the effect of fluctuations in waist circumference (WC), weight, and body mass index (BMI) on the incidence of diabetes in older adults. PATIENTS AND
methodsA prospective cohort of 61,587 older adults (age, 60-96 years) who did not have diabetes at study initiation was examined. Data on weight, BMI, and WC were collected, and participants were followed up until 31 December 2018. The main end point was new-onset diabetes. A Cox regression model was used to estimate the risk of diabetes (hazard ratios [HRs] and confidence intervals [CI]) in these participants.
resultsDuring a mean follow-up of 3.6 years, being overweight (HR [95% CI] 1.87 [1.62-2.17]), obesity (1.41 [1.26-1.59]), abdominal obesity (1.42 [1.28-1.58]), and obesity plus abdominal obesity at baseline (1.93 [1.66-2.25]) increased the risk of diabetes onset. Compared with older adults who "maintained normal WC", those who "remained abdominally obese" (HR = 1.66), "became abdominally obese" (HR = 1.58), or "achieved normal WC" (HR = 1.36) were at a higher risk of diabetes onset, as well as those with an increase in WC > 3 cm or > 5% compared with the baseline level. Weight gain or loss > 6 kg or weight gain > 5%, increase or decrease in BMI > 2 kg/m
conclusionFor older adults, WC, BMI, and healthy weight maintenance reduce the diabetes risk. The findings may provide evidence for developing guidelines of proper weight and WC control for older adults.
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