Evidence map›Paper›PMID 34774068›Full record

ArticleJournal of translational medicine2021

Monitoring the tissue perfusion during hemorrhagic shock and resuscitation: tissue-to-arterial carbon dioxide partial pressure gradient in a pig model.

Yusuke Endo, Taku Hirokawa, Taku Miyasho, Ryosuke Takegawa, Koichiro Shinozaki, Daniel M Rolston, Lance B Becker, Kei Hayashida

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Dynamic pathophysiological features of early primary blast lung injury: a novel functional incapacity pig model.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yusuke EndoThe Feinstein Institutes for Medical Research, Northwell Health System, 350 Community Drive, Manhasset, NY, 11030, USA.
Taku HirokawaSchool of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Taku MiyashoSchool of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Ryosuke TakegawaThe Feinstein Institutes for Medical Research, Northwell Health System, 350 Community Drive, Manhasset, NY, 11030, USA.
Koichiro ShinozakiThe Feinstein Institutes for Medical Research, Northwell Health System, 350 Community Drive, Manhasset, NY, 11030, USA.
Daniel M RolstonDepartment of Emergency Medicine, North Shore University Hospital, Northwell Health, Manhasset, NY, USA.
Lance B BeckerThe Feinstein Institutes for Medical Research, Northwell Health System, 350 Community Drive, Manhasset, NY, 11030, USA.
Kei HayashidaThe Feinstein Institutes for Medical Research, Northwell Health System, 350 Community Drive, Manhasset, NY, 11030, USA. khayashida@northwell.edu.ORCID 0000-0002-2287-3318
Northwell Health · USRakuno Gakuen University · JP

Funding

kakenhi 21K16596
6 · The paper itself

Abstract

backgroundDespite much evidence supporting the monitoring of the divergence of transcutaneous partial pressure of carbon dioxide (tcPCO

methodsThis prospective animal study was performed using female pigs at a university-based experimental laboratory. Progressive massive hemorrhagic shock was induced in mechanically ventilated pigs by stepwise blood withdrawal. All animals were then resuscitated by transfusing the stored blood in stages. A transcutaneous monitor was attached to their ears to measure tcPCO

resultsHemorrhage and blood transfusion precisely impacted hemodynamic and laboratory data as expected. The tc-artPCO

conclusionsOur observations suggest the less-invasive tc-artPCO

Indexed as

Shock, HemorrhagicAnimalsCarbon DioxideFemaleOxygenPartial PressurePerfusionProspective StudiesResuscitationSwineCarbon DioxideOxygenCatheterizationHemorrhageHemorrhagic shockResuscitationTranscutaneous partial pressure monitoring of carbon dioxide partial pressureTranscutaneous partial pressure monitoring of oxygen

Identifiers

PMID34774068
PMCPMC8590759
OpenAlexW3182020737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.