Evidence map›Paper›PMID 34774056›Full record

ArticleBMC endocrine disorders2021

Obstructive sleep apnoea and 12-month weight loss in adults with class 3 obesity attending a multidisciplinary weight management program.

Sophie Kobuch, Fiona Tsang, Ritesh Chimoriya, Daniel Gossayn, Sarah O'Brien, Javeria Jamal, Leon Laks, Abd Tahrani, Nic Kormas, Milan K Piya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC endocrine disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Sophie KobuchSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.
Fiona TsangSouth Western Sydney Metabolic Rehabilitation and Bariatric Program, Camden and Campbelltown Hospitals, Campbelltown, New South Wales, Australia.
Ritesh ChimoriyaSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.
Daniel GossaynSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.
Sarah O'BrienSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.
Javeria JamalSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.
Leon LaksAustralian Sleep Diagnostics, Campbelltown, New South Wales, Australia.
Abd TahraniInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
Nic KormasSouth Western Sydney Metabolic Rehabilitation and Bariatric Program, Camden and Campbelltown Hospitals, Campbelltown, New South Wales, Australia.
Milan K PiyaSchool of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia. m.piya@westernsydney.edu.au.
Camden and Campbelltown Hospitals · AUUniversity of Birmingham · GB

Funding

Western Sydney University, Australia Internal Departmental Funds
6 · The paper itself

Abstract

backgroundAlthough there is a strong association between obesity and obstructive sleep apnoea (OSA), the effects of OSA and CPAP therapy on weight loss are less well known. The aim of this study in adults with class 3 obesity attending a multidisciplinary weight management program was to assess the relationship between OSA and CPAP usage, and 12-month weight change.

methodsA retrospective cohort study of all patients commencing an intensive multidisciplinary publicly funded weight management program in Sydney, Australia, between March 2018 and March 2019. OSA was diagnosed using laboratory overnight sleep studies. Demographic and clinical data, and use of CPAP therapy was collected at baseline and 12 months. CPAP use was confirmed if used ≥4 h on average per night on download.

resultsOf the 178 patients who joined the program, 111 (62.4 %) completed 12 months in the program. At baseline, 63.1 % (n=70) of patients had OSA, of whom 54.3 % (n=38) were using CPAP. The non-OSA group had more females compared to the OSA with CPAP group and OSA without CPAP group (90.2 % vs. 57.9 % and 62.5 %, respectively; p=0.003), but there were no significant baseline differences in BMI (50.4±9.3 vs. 52.1±8.7 and 50.3±9.5 kg/m

conclusionsThis multidisciplinary weight management program resulted in significant weight loss at 12 months, regardless of OSA diagnosis or CPAP use in adults with class 3 obesity. Larger studies are needed to further investigate the effects of severity of OSA status and CPAP use in weight management programs. Until completed, this study suggests that the focus should remain on implementing lifestyle changes and weight management regardless of OSA status.

Indexed as

Weight LossAdultAgedCase-Control StudiesCholesterolContinuous Positive Airway PressureDiabetes Mellitus, Type 2FemaleHumansHypoglycemic AgentsLipoproteins, HDLLipoproteins, LDLMaleMiddle AgedObesity, MorbidSleep Apnea, ObstructiveCholesterolHypoglycemic AgentsLipoproteins, HDLLipoproteins, LDLTriglyceridesClass 3 obesityContinuous positive airway pressure (CPAP)Obstructive sleep apnoeaWeight management

Identifiers

PMID34774056
PMCPMC8590787
OpenAlexW3214376828

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.