ArticleBMC medical imaging2021
Impact of time of flight and point spread function on quantitative parameters of lung lesions in
Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Reconstruction robustness of liver-referenced adaptive thresholding forAnnals of nuclear medicine · 2026Article
- Optimization of a Q.Clear PET image reconstruction based on bayesian optimization in oncology and neurology applications.Physical and engineering sciences in medicine · 2026Article
- Toward an optimized PET reconstruction protocol for spinal cord: superiority of OSEM with TOF and PSF.EJNMMI physics · 2026Article
- Deep learning-based restoration of PET images from a dual-panel breast dedicated scanner.Zeitschrift fur medizinische Physik · 2026Article
- Enhancing reader confidence through dual-time imaging and alternative reconstruction algorithms with [EJNMMI research · 2026Article
- Diagnostic accuracy of dual-phaseScientific reports · 2025Article
- Comparison ofEJNMMI physics · 2025Article
- Distribution and predictors of F-18-FDG uptake values of non-malignant cervical lymph nodes in pediatric patients.EJNMMI research · 2024Article
- Quantitative and clinical implications of the EARL2 versus EARL1 [EJNMMI research · 2023Article
- Development of a bespoke phantom to optimize molecular PET imaging of pituitary tumors.EJNMMI physics · 2023Article
- The reproducibility of MTV and TLG of soft tissue tumors calculated by FDG-PET: Comparison between the lower limit by the fixed value SUV 2.5 and that value by 30% of SUVmax.Japanese journal of radiology · 2023Article
- Investigation of tumor assessment between two PET systems using various indices: comparison between PET/CT and PET/MRI systems.American journal of nuclear medicine and molecular imaging · 2023Article
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4 authors.
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Abstract
backgroundImage reconstruction algorithm is one of the important factors affecting the quantitative parameters of PET/CT. The purpose of this study was to investigate the effects of time of flight (TOF) and point spread function (PSF) on quantitative parameters of lung lesions in
methodsThis retrospective study evaluated 60 lung lesions in 39 patients who had undergone
resultsCompared with OSEM reconstruction, using OSEM + TOF + PSF increased SUVmean and SUVmax by 23.73% and 22.71% respectively, and SNR increased by 70.18%, MTV decreased by 23.84% (p < 0.01). The percentage difference was significantly higher in smaller lesions (diameter 10-22 mm) than in larger lesions (diameter 23-44 mm), and significantly higher in low contrast lesions (SNR ≤ 15.31) than in high contrast lesions (SNR > 15.31). The difference of TLG among various reconstruction algorithms is relatively small, the highest value is - 6.48% of OSEM + TOF + PSF, and the lowest value is 0.81% of OSEM + TOF.
conclusionTOF and PSF significantly affected the quantitative parameters of lung lesions in
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