Evidence map›Paper›PMID 34773920›Full record

GuidelineThrombosis and haemostasis2022

2021 Focused Update Consensus Guidelines of the Asia Pacific Heart Rhythm Society on Stroke Prevention in Atrial Fibrillation: Executive Summary.

Tze-Fan Chao, Boyoung Joung, Yoshihide Takahashi, Toon Wei Lim, Eue-Keun Choi, Yi-Hsin Chan, Yutao Guo, Charn Sriratanasathavorn, Seil Oh, Ken Okumura and 1 more

Abstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Thrombosis and haemostasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 244 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
244citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

244 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Clinical service organisation for adults with atrial fibrillation.The Cochrane database of systematic reviews · 2024
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  4. Comparisons of effectiveness and safety between on-label dosing, off-label underdosing, and off-label overdosing in Asian and non-Asian atrial fibrillation patients treated with rivaroxaban: a systematic review and meta-analysis of observational studies.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
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  19. Development and validation of a prediction model for ischemic stroke recurrence risk in patients with ischemic stroke and atrial fibrillation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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184 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tze-Fan ChaoDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Boyoung JoungDivision of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yoshihide TakahashiThe Department of Advanced Arrhythmia Research, Tokyo Medical and Dental University, Tokyo, Japan.
Toon Wei LimNational University Heart Centre, National University Hospital, Singapore.
Eue-Keun ChoiDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yi-Hsin ChanMicroscopy Core Laboratory, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.
Yutao GuoPulmonary Vessel and Thrombotic Disease, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-7626-7751
Charn SriratanasathavornHer Majesty Cardiac Center, Siriraj, Thailand.
Seil OhDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Ken OkumuraDivision of Cardiology, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool & Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.ORCID 0000-0002-7566-1626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The consensus of the Asia Pacific Heart Rhythm Society (APHRS) on stroke prevention in atrial fibrillation (AF) has been published in 2017 which provided useful clinical guidance for cardiologists, neurologists, geriatricians, and general practitioners in the Asia-Pacific region. In these years, many important new data regarding stroke prevention in AF were reported. The practice guidelines subcommittee members comprehensively reviewed updated information on stroke prevention in AF, and summarized them in this 2021 focused update of the 2017 consensus guidelines of the APHRS on stroke prevention in AF. We highlighted and focused on several issues, including the importance of the AF Better Care pathway, the advantages of non-vitamin K antagonist oral anticoagulants (NOACs) for Asians, the considerations of use of NOACs for Asian AF patients with single one stroke risk factor beyond gender, the role of lifestyle factors on stroke risk, the use of oral anticoagulants during the "coronavirus disease 2019" pandemic, etc. We fully realize that there are gaps, unaddressed questions, and many areas of uncertainty and debate in the current knowledge of AF, and the physician's decision remains the most important factor in the management of AF.

Indexed as

AnticoagulantsAtrial FibrillationStrokeAcute Coronary SyndromeAdministration, OralAsiaCatheter AblationFemaleHeart Disease Risk FactorsHemorrhageHolistic HealthHumansMalePercutaneous Coronary InterventionRisk AssessmentSARS-CoV-2Anticoagulants

Identifiers

PMID34773920
PMCPMC8763451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.