Evidence map›Paper›PMID 34773515›Full record

ReviewPlanta2021

Nitro-fatty acids: electrophilic signaling molecules in plant physiology.

Luciano Di Fino, Andrés Arruebarrena Di Palma, Enzo A Perk, Carlos García-Mata, Francisco J Schopfer, Ana M Laxalt

Abstract readReview
In one paragraph

Review in Planta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luciano Di FinoInstituto de Investigaciones Biológicas, CONICET-Universidad Nacional de Mar del Plata, Mar del Plata, Argentina.
Andrés Arruebarrena Di PalmaInstituto de Investigaciones Biológicas, CONICET-Universidad Nacional de Mar del Plata, Mar del Plata, Argentina.
Enzo A PerkInstituto de Investigaciones Biológicas, CONICET-Universidad Nacional de Mar del Plata, Mar del Plata, Argentina.
Carlos García-MataInstituto de Investigaciones Biológicas, CONICET-Universidad Nacional de Mar del Plata, Mar del Plata, Argentina.
Francisco J SchopferDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.
Ana M LaxaltInstituto de Investigaciones Biológicas, CONICET-Universidad Nacional de Mar del Plata, Mar del Plata, Argentina. amlaxalt@mdp.edu.ar.ORCID http://orcid.org/0000-0002-8225-2441

Funding

Formation and metabolism of nitrated fatty acidsR01GM125944 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHOPFER, FRANCISCO JOSE · 2018 to 2025
$3.4M
Predominant protective role in hepatic steatosis and obesity by fish oil-derived furansR01DK112854 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHOPFER, FRANCISCO JOSE · 2018 to 2021
$1.6M
NIDDK NIH HHS R01 DK112854NIGMS NIH HHS R01 GM125944NIH HHS DK112854NIH HHS GM125944
6 · The paper itself

Abstract

MAIN

conclusionNitro fatty acids (NO2-FA)have relevant physiological roles as signaling molecules in biotic and abiotic stress, growth, and development, but the mechanism of action remains controversial. The two main mechanisms involving nitric oxide release and thiol modification are discussed. Fatty acids (FAs) are major components of membranes and contribute to cellular energetic demands. Besides, FAs are precursors of signaling molecules, including oxylipins and other oxidized fatty acids derived from the activity of lipoxygenases. In addition, non-canonical modified fatty acids, such as nitro-fatty acids (NO

Indexed as

Fatty AcidsNitric OxideAnimalsPlant Physiological PhenomenaReactive Nitrogen SpeciesSignal TransductionFatty AcidsNitric OxideReactive Nitrogen SpeciesNitric oxideNitro-fatty acidsReactive nitrogen species

Identifiers

PMID34773515
PMCPMC10704571

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.