Evidence map›Paper›PMID 34773514›Full record

ArticleMedical molecular morphology2022

Nicorandil, an ATP-sensitive potassium channel activation, attenuates myocardial injury in rats with ischemic cardiomyopathy.

Li Shaoqing, Zhao Ting, Liu Hao, Zhihui He, Yu Wang, Zhao Ming

Abstract read
PubMed Publisher
In one paragraph

Article in Medical molecular morphology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Li Shaoqing *Cangzhou Central Hospital, Cangzhou, 061000, Hebei, China.
Zhao Ting *College of Basic Medical Sciences, Jilin University, Changchun, 130021, China.ORCID http://orcid.org/0000-0003-1757-0934
Liu HaoInner Mongolia University for the Nationalities, Tongliao, Inner Mongolia, People's Republic of China.
Zhihui HeInner Mongolia University for the Nationalities, Tongliao, Inner Mongolia, People's Republic of China.
Yu WangInner Mongolia University for the Nationalities, Tongliao, Inner Mongolia, People's Republic of China. shen348@126.com.
Zhao MingInner Mongolia University for the Nationalities, Tongliao, Inner Mongolia, People's Republic of China. langzhe73@163.com.
Inner Mongolia University for Nationalities · CNCangzhou Central Hospital · CNJilin University · CN

Funding

Inner Mongolia University for Nationalities NMDYB19071Natural Science Foundation of Inner Mongolia Autonomous Region 2017MS (LH) 0824
6 · The paper itself

Abstract

Ischemic cardiomyopathy is a common but underestimated cause of heart failure. This study investigated the myocardial-protective effects of nicorandil on rats with ischemic cardiomyopathy. In the present study, ischemic cardiomyopathy rats model were used to evaluate the effects of nicorandil. Cardiac ultrasonography was employed to examine the changes of heart structure and heart function. Electron microscopy was employed to observe the changes of pathological ultrastructure of the myocardium. Western blot and enzyme-linked immunosorbent assays were employed to detect protein levels and Mitochondrial Ca

Indexed as

CardiomyopathiesMyocardial IschemiaAnimalsKATP ChannelsMyocardiumNicorandilRatsKATP ChannelsNicorandilATP-sensitive potassium channelIschemic cardiomyopathyMitochondrial dynamicsNicorandil

Identifiers

PMID34773514
OpenAlexW3211741340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.