Evidence map›Paper›PMID 34773473›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Comparing the clinical performance and cost efficacy of [

Ian Alberts, Clemens Mingels, Helle D Zacho, Sabine Lanz, Heiko Schöder, Axel Rominger, Marcel Zwahlen, Ali Afshar-Oromieh

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  2. Comparison ofProstate cancer and prostatic diseases · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Evaluating [Journal of market access & health policy · 2026
    Article
  7. Review
  8. Review
  9. Comparison of early and standardAnnals of nuclear medicine · 2025
    Article
  10. Article
  11. Update on PSMA-based Prostate Cancer Imaging.Seminars in nuclear medicine · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Comparison between [International journal of molecular sciences · 2023
    Article
  16. Article
  17. The Role of [Cancers · 2022
    Review
  18. Assessment of malignancy and PSMA expression of uncertain bone foci in [European journal of nuclear medicine and molecular imaging · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ian AlbertsDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland. ian.alberts@insel.ch.
Clemens MingelsDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.
Helle D ZachoInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Sabine LanzDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.
Heiko SchöderInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Axel RomingerDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.
Marcel ZwahlenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Ali Afshar-OromiehDepartment of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeAmongst others, [

methodsTwo hundred and forty-four patients undergoing PSMA PET/CT for rPC were retrospectively analysed for this study (one hundred and twenty two with each radiopharmaceutical) to generate rates of PET positivity, negativity and unclear findings. Patients underwent follow-up to determine the rate of additional examinations and to confirm PET findings. A Markov chain decision analysis was implemented to model clinical decision-making processes and to analyse clinical performance of the two tracers. We determine their clinical cost efficacies using cost data from several countries where both radiotracers are in routine use.

resultsThe PET positivity rate was non-significantly higher for [

conclusionThe analysis reveals a non-significantly higher PET positivity rate for [

Indexed as

Gallium RadioisotopesProstatic NeoplasmsDecision Support TechniquesEdetic AcidFluorine RadioisotopesGallium IsotopesHumansMaleMarkov ChainsNeoplasm Recurrence, LocalNiacinamideOligopeptidesPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesEdetic AcidFluorine-18Fluorine Radioisotopesgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesNiacinamideOligopeptidesPSMA-1007RadiopharmaceuticalsMarkov chain analysisPET/CTPositron emission tomographyPSMARecurrent prostate cancer

Identifiers

PMID34773473
PMCPMC9525363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.